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Table 2 Postoperative antibiotic concentration

From: Does the use of a closed-suction drain reduce the effectiveness of an antibiotic-loaded spacer in two-stage exchange Arthroplasty for Periprosthetic hip infection? A prospective, randomized, controlled study

 

Study group

Control group

P-value

Vancomycin concentration (M ± SD)

 Day 1

273.26 ± 31.93

260.85 ± 11.88

0.156

 Day 2

214.39 ± 47.19

199.90 ± 41.68

0.365

 Day 3

165.39 ± 57.49

173.02 ± 35.36

0.654

 Day 4

131.92 ± 57.28

122.16 ± 47.73

0.604

 Day 5

110.13 ± 66.78

98.52 ± 40.31

0.556

 Change

163.20 ± 77.05

162.39 ± 36.31

0.917

Meropenem concentration (M ± SD)

 Day 1

134.04 ± 20.59

126.61 ± 14.56

0.248

 Day 2

63.99 ± 27.28

56.84 ± 16.36

0.375

 Day 3

18.09 ± 5.88

19.35 ± 6.86

0.581

 Day 4

11.78 ± 2.79

10.93 ± 1.88

0.318

 Day 5

10.27 ± 3.26

9.34 ± 8.40

0.682

 Change

123.78 ± 21.04

117.27 ± 19.38

0.548