Table 3 Univariate and multivariate analyses for CSS for patients identified in the SEER Program database from 1973 to 2015

Age

≤16

/

1

/

1

17–39

0.192

2.243 (0.666–7.554)

0.1

2.803 (0.822–9.556)

40–60

0.206

2.153 (0.655–7.074)

0.183

2.271 (0.679–7.601)

>60

0.032*

3.569 (1.112–11.454)

0.03*

3.863 (1.14–13.091)

Sex

Male

/

1

Female

0.427

0.854 (0.578–1.261)

Decade of diagnosis

1970s

/

1

1980s

0.82

1.088 (0.526–2.249)

1990s

0.447

1.323 (0.643–2.72)

2000s

0.358

0.726 (0.367–1.437)

2010s

0.514

0.755 (0.324–1.759)

Race recode

Other

/

1

White

0.853

1.076 (0.497–2.329)

Black

0.28

1.633 (0.671–3.974)

Tumor Grade

High

/

1

Low

0.101

1.859 (0.885–3.905)

Unknown

0.06

2.079 (0.969–4.464)

Tumor type

Fibrosarcoma (NOS)

/

1

Fibromyxosarcoma

0.436

0.45 (0.061–3.351)

Periosteal fibrosarcoma

0.571

0.754 (0.284–2.004)

Malignant fibrous histiocytoma

0.864

1.043 (0.643–1.693)

Tumor Size

<5 cm

/

1

/

1

5 cm-10

0.163

1.446 (0.861–2.426)

0.205

1.908 (0.703–5.176)

>10

< 0.001*

7.595 (4.553–12.671)

0.033*

3.075 (1.092–8.659)

Unknown

0.08

2.108 (0.914–4.863)

0.082

2.314 (0.899–5.951)

Tumor sequence

First

/

1

/

1

≥Second

0.023*

0.042 (0.003–0.641)

0.943

0

Stage

local

/

1

/

1

region

0.128

1.355 (0.916–2.004)

0.145

1.481 (0.873–2.514)

distant

< 0.001*

5.383 (3.517–8.237)

< 0.001*

4.401 (2.47–7.841)

unknown

< 0.001*

2.68 (1.468–4.892)

0.942

0.967 (0.396–2.363)

Surgery

No

/

1

/

1

Yes

< 0.001*

0.226 (0.15–0.34)

< 0.001*

0.318 (0.191–0.527)

unknown

0.963

0

0.989

0

Radiotherapy

no/unknown

/

1

/

1

Yes

0.02*

1.652 (1.084–2.517)

0.589

0.878 (0.546–1.409)

Chemotherapy

no/unkown

/

1

/

1

yes

0.481

0.87 (0.59–1.282)

0.871

0.963 (0.609–1.523)