Table 2 Univariate and multivariate analyses for OS for patients identified in the SEER Program database from 1973 to 2015

Age

≤16

/

1

/

1

17–39

0.124

2.562

0.098

2.765 (0.827–9.243)

40–60

0.037*

3.47 (1.075–11.202)

0.027*

3.81 (1.163–12.486)

>60

0.001*

7.381 (2.323–23.45)

0.004*

5.688 (1.722–18.782)

Sex

Male

/

1

Female

0.276

0.840 (0.613–1.150)

Decade of diagnosis

1970s

/

1

1980s

0.938

0.977 (0.552–1.731)

1990s

0.204

1.444 (0.819–2.545)

2000s

0.382

0.784 (0.454–1.353)

2010s

0.999

1 (0.512–1.954)

Race recode

Other

/

1

White

0.435

1.293 (0.679–2.462)

Black

0.505

1.301 (0.6–2.822)

Tumor Grade

Low

/

1

High

0.065

1.691 (0.968–2.954)

Unknown

0.02*

1.97 (1.115–3.48)

Tumor type

Fibrosarcoma (NOS)

/

1

Fibromyxosarcoma

0.188

0.263 (0.036–1.923)

Periosteal fibrosarcoma

0.249

0.649 (0.311–1.354)

Malignant fibrous histiocytoma

0.609

0.906 (0.621–1.322)

Tumor Size

<5 cm

/

1

/

1

5 cm-10

0.109

1.889 (0.868–4.114)

0.034*

2.335 (1.065–5.124)

>10

< 0.001*

4.714 (2.111–10.527)

0.001*

4.051 (1.769–9.275)

Unknown

< 0.001*

3.301 (1.602–6.801)

0.027*

2.324 (1.1–4.91)

Tumor sequence

First

/

1

/

1

≥Second

0.031*

1.618 (1.045–2.505)

0.142

1.425 (0.889–2.287)

Stage

Local

/

1

/

1

region

0.128

1.355 (0.916–2.004)

0.091

1.421 (0.945–2.135)

distant

< 0.001*

5.383 (3.517–8.237)

< 0.001*

3.917 (2.427–6.321)

unknown

< 0.001*

2.68 (1.468–4.892)

0.515

1.239 (0.65–2.359)

Surgery

No

/

1

/

1

Yes

< 0.001*

0.267 (0.19–0.376)

< 0.001*

0.397 (0.262–0.6)

unknown

0.408

0.433 (0.06–3.144)

0.528

0.515 (0.066–4.05)

Radiotherapy

no/unknown

/

1

/

1

Yes

0.003*

1.684 (1.196–2.371)

0.831

0.959 (0.655–1.404)

Chemotherapy

no/unknown

/

1

/

1

Yes

0.023*

0.688 (0.499–0.949)

0.282

0.816 (0.563–1.182)