TY - JOUR AU - Oda, Takahiro AU - Niikura, Takahiro AU - Fukui, Tomoaki AU - Arakura, Michio AU - Oe, Keisuke AU - Mifune, Yutaka AU - Hayashi, Shinya AU - Matsumoto, Tomoyuki AU - Matsushita, Takehiko AU - Kuroda, Ryosuke PY - 2019 DA - 2019/12/12 TI - Ras associated with diabetes may play a role in fracture nonunion development in rats JO - BMC Musculoskeletal Disorders SP - 602 VL - 20 IS - 1 AB - Rad is the prototypic member of a subfamily of Ras-related small G-proteins and is highly expressed in the skeletal muscle of patients with type II diabetes. Our previous microarray analysis suggested that Rad may mediate fracture nonunion development. Thus, the present study used rat experimental models to investigate and compare the gene and protein expression patterns of both Rad and Rem1, another RGK subfamily member, in nonunions and standard healing fractures. SN - 1471-2474 UR - https://doi.org/10.1186/s12891-019-2970-9 DO - 10.1186/s12891-019-2970-9 ID - Oda2019 ER -