Certainty assessment | № of (events/) participants | Quality | Importance | ||||||
---|---|---|---|---|---|---|---|---|---|
№ of studies | Risk of bias | Inconsistency | Indirectness | Imprecision | Publication bias | Intervention | Control | Overall certainty of evidence | Importance of outcomesa |
Pain (follow up: from 2 weeks to 3 months; assessed with: Visual Analogue Scale) | |||||||||
Seriousf | Not serious | Not serious | Not serious | Nonem | 204 | 205 | ⨁⨁◯◯ Moderate | Critical | |
Function (follow up: range from 2 weeks to 3 months; assessed with: Timed Up and Go test) | |||||||||
Seriousf | Serioush | Not serious | Seriousi | Nonem | 103 | 104 | ⨁◯◯◯ Very low | Critical | |
Mobility (follow up: range from 2 months to 3 months; assessed with: Six-Minute Walk Test) | |||||||||
Seriousf | Serioush | Seriousg | Very seriousi, l | Nonem | 128 | 130 | ⨁⨁◯◯ Very low | Critical | |
Serious adverse eventsb (follow up: range 6 weeks to 4 months) | |||||||||
Not serious | Not serious | Seriousj | Not serious | Nonem | 38/334 (11.4%) | 27/333 (8.1%)d | ⨁⨁⨁◯ Moderate | Critical | |
Treatment-related adverse eventsc (follow up: range 6 weeks to 4 months) | |||||||||
Not serious | Not assessedk | Not serious | Not assessedk | Nonem | 9/251 (3.1%) | 8/256 (3.6%)e | ⨁⨁⨁◯ Moderate | Critical |