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Table 3 ROC curves comparing the ccf n-DNA and mt-DNA to discriminate AIS patients and controls

From: Changes in circulating cell-free nuclear DNA and mitochondrial DNA of patients with adolescent idiopathic scoliosis

Test Cutoff (GE/ml) AUC (95% CI) Sensitivity Specificity P value
n-DNA-GAPDH 732 0.589 (0.456–0.722) 0.551 0.667 0.217
n-DNA-ACTB 6953 0.657 (0.525–0.789) 0.710 0.619 0.030
mt-DNA 1,684,972 0.562 (0.440–0.683) 0.319 0.905 0.393
  1. Abbreviation: ccf cell free circulating, AUC area under curves