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Table 3 ROC curves comparing the ccf n-DNA and mt-DNA to discriminate AIS patients and controls

From: Changes in circulating cell-free nuclear DNA and mitochondrial DNA of patients with adolescent idiopathic scoliosis

Test

Cutoff (GE/ml)

AUC (95% CI)

Sensitivity

Specificity

P value

n-DNA-GAPDH

732

0.589 (0.456–0.722)

0.551

0.667

0.217

n-DNA-ACTB

6953

0.657 (0.525–0.789)

0.710

0.619

0.030

mt-DNA

1,684,972

0.562 (0.440–0.683)

0.319

0.905

0.393

  1. Abbreviation: ccf cell free circulating, AUC area under curves
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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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