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Fig. 1 | BMC Musculoskeletal Disorders

Fig. 1

From: Exercise-induced pain changes associate with changes in muscle perfusion in knee osteoarthritis: exploratory outcome analyses of a randomised controlled trial

Fig. 1

DCE-MRI analysis. DCE-MRI analysis is based on changes in signal intensity over time for each voxel within the VOI. The signal intensity changes calculated relatively to the baseline signal intensity and the changes over time can be plotted as time-intensity-curves (TICs): a TIC from a point of interest in the popliteal artery with the characteristics of tissue with high perfusion: rapid increase in signal intensity, which reaches a plateau and a subsequent rapid decrease (washout) (x-axis: time (s); y-axis: relative signal intensity (baseline = 1.0)). IRE: Initial Rate of Enhancement; ME: Maximal Enhancement; IRW: initial rate of washout. b Assignment and color–coding of the voxels within the ROIs based on the shape of the TICs: No enhancement (no color); Persistent (blue); Plateau (green) and Washout (red) represent the most perfused voxels. c Region of interests (ROIs) around the peri-articular knee muscles avoiding major vascular branches. Blue: extensor muscle; Yellow: flexor muscles. d Parametric map of Initial Rate of Enhancement. Brighter colors indicate higher values

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BMC Musculoskeletal Disorders

ISSN: 1471-2474

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