Table 1 Characteristics of studies included in this meta-analysis
Studies | Animals | No. of animals (con/v) | Fracture site | Fracture model | Treatment group | Control group | Treatment duration | Outcomes |
|---|---|---|---|---|---|---|---|---|
Yu, Zr 2012 [15] | SD rats, female, 3-month-old | 8/8/8 | femur | OVX, fracture | BMSCs, BMSCs+PLGA/COL microspheres | SHAM | 3 months | BMD, (BV/TV), (Tb.Sp) |
XU ZW 2013 [16] | SD rats, female, (350±8.695)g | 18/18/18 | tibia | OVX, fracture | BMSCs, BMSCs+Drynaria fortunei extraction | Blank | 7/14/28/40 days | BMD |
Liu,X 2016 [17] | SD rats, female, (180-220)g | 12/12/12 | mandibles | OVX, fracture | BMSCs/HA, OPG-BMSCs/HA | HA | 4/6/8 weeks | BMD |
Li, KC 2016 [18] | SD rats, female, 8-week-old | 8/8/6 | femur | OVX, fracture | BMSCs, BMSCs+214S | SHAM | 2/4 weeks | BMD,(BV/TV),(Tb.Sp) |
Xu, RY 2016 [19] | SD rats, female, 3-month-old | 5/5 | mandibles | OVX, fracture | BMSCs | SHAM | 12 weeks | (BV/TV), (Tb.Sp) |