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Table 3 Relative difference in functional measures between the case- and control-group within each ICF-dimension

From: Relative difference among 27 functional measures in patients with knee osteoarthritis: an exploratory cross-sectional case-control study

ICF Variables Cases
(n = 28)
Controls (n = 31) ES or Med d ES or Med d 95% CI Stats
t, χ2, U, M
P E Abs ES or C’s d
Body Function Pain last wk., Med (IQR) (R) 3.5 (4.8) 0.0 (1.0) 3.0 3.0, 5.0 0.000 (U) 2.0E-12§ 3.3
KOOS Pain, Med (IQR) 58.8 (18.8) 98.4 (3.6) −38.9 −52.8, −30.6 5.0 (U) 1.8E-11§ 3.2
KOOS Symptoms, Med (IQR) 58.9 (33.9) 98.4 (3.6) −35.8 −42.9, −28.6 4.0 (U) 4.6E-11§ 3.2
Pain-10StUpDw, Med (IQR) (R) 2.0 (3.0) 0.0 (3.0) 2.0 1.0, 3.0 108 (U) 1.7E-08§ 1.7
Pain-30sCST, Med (IQR) 2.0 (5.0) 0.0 (0.1) 2.0 1.0, 4.0 124 (U) 2.4E-08§ 1.6
Pain-6MWT, Med (IQR) (R) 3.5 (6.8) 0.0 (3.0) 2.0 0.0, 5.0 130 (U) 0.00061‡ 1.5
Pain-TUG, Med (IQR) 0.1 (2.7) 0.0 (0.1) 0.2 0.0, 1.0 217 (U) 1.0E-5‡ 0.9
Knee ext. strength inv. leg, M (SD) 1.16 (0.48) 1.46 (0.38) −0.7 −0.2, −1.2 1.592 (t) 0.010* 0.7
30sTSLS inv. leg (s), Med (IQR) 11.0 (25.4) 29.8 (7.3) −9.1 −21.1, 0.0 292 (U) 0.0291* 0.6
30sCST (n), M (SD) 14.0 (4.2) 16.3 (4.2) −0.5 − 1.1, 0.0 −2.1 (t) 0.0422 0.5
Knee ext. stren., uninv. leg, M (SD) 1.45 (0.36) 1.64 (0.46) −0.5 −1.0, 0.1 − 1.74 (t) 0.088 0.5
TSLS uninv leg (s), Med (IQR) 15.9 (23.5) 29.5 (16.0) −5.4 −14.1, 0.0 329 (U) 0.1071 0.4
RPE-6MWT, M (SD) 6.0 (1.8) 5.5 (1.7) 0.3 −0.2, 0.8 1.1 (t) 0.2577 0.3
  RPE-10StUpDwT, M (SD) 3.3 (1.7) 3.1 (1.3) 0.2 −0.3, 0.7 0.6 (t) 0.5368 0.2
  RPE-30sCST, Med (IQR) 3.0 (3.0) 3.0 (2.0) 0.0 −1.0, 1.0 420 (U) 0.8266 0.1
Activity KOOS Sport/Rec, Med (IQR) 30.0 (25.6) 100 (5.0) −65.0 −75.0, −60.0 4.0 (U) 2.3E-11§ 3.2
KOOS ADL, Med (IQR) (R) 67.7 (39.6) 100.0 (13.9) −32.4 −38.2, −14.7 28.5 (U) 9.5E-11§ 2.7
10StUpDwT (s), M (SD) 10.8 (3.1) 7.8 (1.1) 1.3 0.7, 1.9 5.0 (t) 3.6E-05‡ 1.3
Timed Up-and-Go (s), M (SD) 6.6 (1.2) 5.7 (0.9) 0.9 0.3, 1.4 3.4 (t) 0.0014† 0.9
6MWT (m), M (SD) 642.5 (94.6) 717.4 (75.4) −0.9 −1.4, −0.3 −3.4 (t) 0.0014† 0.9
Participation KOOS QoL, Med (IQR) (R) 43.8 (25.0) 100.0 (25.0) −56.2 −62.5, −43.8 1.0 (U) 9.8E-12§ 3.3
Örebo PsySoc, M (SD) 39.0 (12.7) 12.8 (9.6) 2.3 1.7, 3.0 9.0 (t) 1.6E-12§ 2.3
Vig.-int. act. (min/wk), Med (IQR) 1.0 (15.3) 29.0 (63.0) −23.0 −46.0, −10 167.5 (U) 4.5E-05‡ 1.2
EUROHIS-QoL, Med (IQR) 33.0 (4.4) 36.0 (6.0) −3.0 −5.0, −1.0 274.5 (U) 0.015* 0.7
Mod.-int. act. (min/wk), M (SD) 286.0 (169.1) 382.5 (134.5) −0.6 −1.2, −0.1 −2.4 (t) 0.018* 0.6
Light-int. act. M (SD) 1553.0 (444.9) 1494.9 (468.6) 0.1 −0.4, 0.6 0.5 (t) 0.63 0.1
Sed.-int. act. (min/wk); M (SD) 8141.9 (663.1) 8197.5 (662.9) −0.1 −0.6, 0.4 −0.3 (t) 0.74 0.1
  1. Notes. Case = patients with knee osteoarthritis, control = individuals without knee complaints; ICF = = the International Classification of Function, Disability, and Health (of the WHO); ES = effect size by Cohen’s d or mean difference between groups divided by the variability of groups; Med d = median difference; CI = confidence interval; Stats = statistics; P = probability value; E = estimated; Abs = absolute value; ES = effect size or Cohen’s d; C’s d = Cohen’s d.; KOOS = Knee Injury and Osteoarthritis Outcome Scale; Med = median; IQR = interquartile range; R = range (given for the controls when the IQR was not obtainable); 10StUpDw = 10 step up-and-down stair climb test; 30sCST = number of Chair-to-Stand raises in 30 s test; 6MWT = test of distance walked in 6 minutes; TUG = Time up-and-go test or seconds taken to rise from a chair, walk 3 m, turn, walk back, and sit down; 30sTSLS inv. leg = 30 s timed single-leg standing on the involved leg; RPE = Rate of Perceived exertion on the Borg Category Rating Scale; Sports/Rec = sports and recreation scale; ADL = activity of daily life; QoL = Quality of Life; PsycSoc. = psychosocial questionnaire; Vig.-int. Act. = Vigorous-intensity physical activity of daily life; Mod. = moderate; Sed. = sedentary; * = significant result, † = highly significant result, ‡ = very highly significant result, § = extremely highly significant result