Advertisement
Table 1 TARGET trial inclusion/exclusion criteria
| Inclusion criteria | Exclusion criteria |
|---|---|
| Aged ≥50 years | Lateral joint space narrowing ≥ medial joint space narrowing on x-ray |
| Report knee pain on most days of the past month | Knee surgery/joint injection in past 6 months or planned surgery in the next 9 months |
| Suffered knee pain for 3 months or more | Current or past (4 weeks) oral corticosteroids |
| Report a minimum average overall pain score of 4 on an 11-point numeric rating scale over the previous week | Systemic arthritic conditions |
| Demonstrate tibiofemoral osteophytes on x-ray | Past knee fracture or malignancy |
| Obesity (BMI = 30 kg/m2 and over) | Past hip/knee joint replacement/tibial osteotomy |
| Have a mobile phone that has text messaging functionality and be happy to receive text message reminders if required during the study | Other condition currently affecting lower limb function |
| Participation in knee strengthening or neuromuscular/functional exercise in past 6 months or planning to start exercise in next 9 months | |
| Unable to walk unaided | |
| Unable to commit to study requirements |
