Study | Number of participants | Withdrawals/dropouts | Intervention Eccentric exercise (painful eccentric exercise) | Control Other exercise types (non-painful eccentric exercise) | Comments |
---|---|---|---|---|---|
Bateman et al. (2014) [38] | I: 4 C1: 4 (concentric group) C2:3 (no exercise) | I: 1 C1: 1 C2: 0 | Oxford Shoulder Score Baseline: 34.0 (SD 5.3) Post-treatment (8 weeks): 31.3 (SD 6.3) Δ − 2.7 | Oxford Shoulder Score Baseline: 24.0 (SD 3.7) Post-treatment (8 weeks): 24.3 (SD 4.2) Δ + 0.3 | Control group 2 (C2) excluded because no treatment was given. Function measured with the 12-item Oxford Shoulder Score. Range 12–60, where 12 indicates no pain and normal function and higher is worse. MID 6 points [43]. |
Between-group difference in change: Δ 3.0; in favor of eccentric exercise (ns) | |||||
Blume et al. (2015) [35] | I: 18 C: 20 | I: 0 C: 4 | DASH Baseline: 25.0 (SD 10.6) Post-treatment (8 weeks): 12.1 (SD 11.7) Δ − 12.9 | DASH Baseline: 21.2 (SD 6.5) Post-treatment (8 weeks): 9.3 (SD 7.1) Δ − 11.9 | Function measured with the 30-item DASH questionnaire. Range 0–150, higher is worse. MID = 10.5 points [40]. |
Between-group difference in change: Δ 1.0; in favor of eccentric exercise (ns) | |||||
Chaconas et al. (2017) [34] | I: 25 C: 21 | I: 0 C: 2 | WORC Baseline: 66.6 (SD 16.0) Post-treatment (6 weeks): 87.6 (SD 14.5) Δ + 21.0 At 6 months: 92.7 (SD 9.0) Δ + 26.1 | WORC Baseline: 65.4 (SD 14.1) Post-treatment (6 weeks): 70.6 (SD 16.8) Δ + 5.2 At 6 months: 77.2 (SD 15.9) Δ + 11.8 | Function measured with WORC. Total range 0–2100 (aggregate score of 6 total sub-domains), here reported as scores out of 100 i.e. a percentage of normal score, where higher is better. MID = 275 points [39]. |
Between-group difference in change at 6 weeks: Δ 17.0; in favor of eccentric exercise (p < 0.001) Between-group difference in change at 6 months: Δ 15.1; in favor of eccentric exercise (p = 0.007) | |||||
Dejaco et al. (2017) [37] | I: 20 C: 16 | I: 1 C: 1 | Constant-Murley Score Baseline: 72.5 (SD 17.7) Post-treatment (12 weeks): 87.3 (SD 16.2) Δ + 14.8 At 6 months: 86.9 (SD 16.8) Δ + 14.4 | Constant-Murley Score Baseline: 78.9 (SD 8.5) Post-treatment (12 weeks): 87.6 (SD 7.8) Δ + 8.7 At 6 months: 88.8 (SD 8.1) Δ + 9.9 | Function measured with Constant-Murley Score. Four subscales (pain, ADL, ROM, strength). Total range 0–100, where 100 indicates excellent shoulder function. MID = 17 points [41]. |
Between-group difference in change at 12 weeks: Δ 6.1; in favor of eccentric exercise (ns) Between-group difference in change at 6 months: Δ 4.5; in favor of eccentric exercise (ns) | |||||
Hallgren et al. (2014) [50] | I: 51 C: 46 | I: 1 C:1 | Constant-Murley Score Baseline: 48.5 (SD 15.0) 1-year follow up: 83.0 (SD 14.0) Δ + 34.5 | Constant-Murley Score Baseline: 43.5 (SD 15.0) 1-year follow up: 76.0 (SD 18.0) Δ + 32.5 | Long-term follow-up of the study by Holmgren et al. 2012. Baseline values from the Holmgren et al. paper. |
Between-group difference in change: Δ 2; in favor of eccentric exercise (ns) | |||||
Holmgren et al. (2012) [26] | I: 51 C: 46 | I: 0 C: 0 | Constant-Murley Score Baseline: 48.5 (SD 15.0) Post-treatment (12 weeks): 72.5 (SD 19.0) Δ + 24 | Constant-Murley Score Baseline: 43.5 (SD 15.0) Post-treatment (12 weeks): 52.5 (SD 23.0) Δ + 9 |  |
Between-group difference in change: Δ 15; in favor of eccentric exercise (95% CI 8.5 to 20.6) | |||||
Maenhout et al. (2013) [25] | I: 31 C: 30 | I: 4 C: 5 | SPADI Baseline: 42.0 (SD 11.0) Post-treatment (12 weeks): 17.0 (SD 11.4) Δ −25.7 | SPADI Baseline: 44.3 (SD 11.5) Post-treatment (12 weeks): 14.5 (SD 11.7) Δ − 27.0 | Measured with SPADI. A 13-item scale (5 items on pain, 8 on disability). Range 0–130, higher is worse. Pain and disability subscales not reported separately. MID = 18 points [40]. |
Between-group difference in change: Δ 1.3; in favor of control (ns) | |||||
Vallés-Carrascosa et al. (2018) [32] | I: 11 C: 11 | I: 0 C: 0 | Constant-Murley Score Baseline: 35.0 (22.0; 47.0) Post-treatment (4 weeks): 59.0 (50.0; 68.0) Δ + 24.0 | Constant-Murley Score Baseline: 36.0 (22.0; 45.0) Post-treatment (4 weeks): 65.0 (55.0; 69.0) Δ + 29.0 | Median (1st;3rd quartile) |
Between-group difference in change: Δ 5; in favor of non-painful eccentric exercise (ns) |