| |
Crude HR (95% CI)
|
Adjusted HR (95% CI)a
|
p-value b
|
|---|
|
Gender
|
|
Female
|
1.02 (0.89–1.16)
|
1.09 (0.94–1.26)
|
0.27
|
|
Age
|
1.00 (0.99–1.01)
|
1.00 (0.99–1.01)
|
0.9
|
|
Year of surgery
|
|
2007–2011
|
1
|
1
|
–
|
|
2012–2016
|
0.94 (0.82–1.09)
|
1.13 (0.96–1.35)
|
0.14
|
|
ASA-classification
|
|
ASA I
|
1
|
1
|
–
|
|
ASA II
|
0.98 (0.85–1.13)
|
1.00 (0.85–1.16)
|
0.9
|
|
ASA III-IV
|
1.24 (0.97–1.60)
|
1.25 (0.94–1.64)
|
0.12
|
|
Diagnosis
|
|
Primary osteoarthritis
|
1
|
1
|
–
|
|
Secondary osteoarthritisc
|
1.04 (0.91–1.20)
|
0.95 (0.81–1.12)
|
0.55
|
|
Surgical approach
|
|
Posterolateral
|
1
|
1
|
–
|
|
Anterior
|
0.52 (0.38–0.71)
|
0.66 (0.47–0.92)
|
0.01
|
|
Direct lateral
|
0.82 (0.70–0.98)
|
0.86 (0.71–1.04)
|
0.12
|
|
Anterolateral
|
1.05 (0.82–1.34)
|
1.16 (0.89–1.52)
|
0.27
|
|
Fixation
|
|
Uncemented
|
1
|
1
|
–
|
|
Cemented
|
1.15 (0.93–1.42)
|
0.91 (0.67–1.23)
|
0.54
|
|
Hybrid
|
1.24 (0.75–2.08)
|
1.32 (0.74–2.35)
|
0.35
|
|
Reversed hybrid
|
1.21 (0.96–1.52)
|
1.19 (0.91–1.55)
|
0.22
|
|
Head Diameter
|
|
32 mm
|
1
|
1
|
–
|
|
22–26 mm
|
1.54 (0.79–2.99)
|
1.49 (0.75–2.99)
|
0.26
|
|
28 mm
|
1.21 (1.03–1.43)
|
1.11 (0.92–1.34)
|
0.28
|
|
36 mm
|
1.02 (0.84–1.23)
|
1.14 (0.92–1.42)
|
0.22
|
|
≥ 38 mm
|
2.85 (2.27–3.57)
|
1.90 (1.33–2.72)
|
< 0.001
|
|
Bearing type
|
|
C-PE
|
1
|
1
|
–
|
|
MoM
|
2.39 (1.94–2.94)
|
1.76 (1.27–2.43)
|
< 0.001
|
|
M-PE
|
1.06 (0.88–1.27)
|
1.02 (0.83–1.26)
|
0.83
|
|
CoC
|
0.77 (0.61–0.97)
|
0.77 (0.60–1.00)
|
0.05
|
|
Zr-PE
|
0.92 (0.67–1.28)
|
0.90 (0.64–1.25)
|
0.52
|
- aMultivariable Cox regression analysis performed with 17,288 observations and 741 events (complete cases); bp-value based on adjusted HR; cincludes dysplasia, osteonecrosis, (acute) fracture, inflammatory arthritis, late posttraumatic, Post-Perthes and rheumatoid arthritis
