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Fig. 6 | BMC Musculoskeletal Disorders

Fig. 6

From: Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis

Fig. 6

(a) Histology images of osteophyte formation (arrows) in loaded joints from WT mice (b) Articular cartilage thickness (LF – lateral femur, LT – lateral tibia, MF – medial femur, MT – medial tibia). MicroCT analysis of the epiphyseal region of the lateral femur (c) subchondral bone plate thickness (SCB Th.) (d) epiphyseal trabecular bone volume/tissue volume (Tb. BV/TV) (e) epiphyseal trabecular number (Tb. N.) (f) epiphyseal trabecular thickness (Tb. Th.) (g) epiphyseal trabecular separation (Tb. Sp.) (h) epiphyseal trabecular pattern factor (Tb. Pf.). i Number of osteoclasts / bone surface. Data are presented as mean ± S.E.M (n > 3/group). P < 0.05*; P < 0.001***

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