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Fig. 2 | BMC Musculoskeletal Disorders

Fig. 2

From: Conditional deletion of E11/podoplanin in bone protects against load-induced osteoarthritis

Fig. 2

(a) Weights of mice treated with Bortezomib or vehicle for days post DMM surgery (b) Maximum OARSI score in the medial and lateral compartments of the left (contralateral control) knee joint of Bortezomib and vehicle treated mice (c) Maximum OARSI score in the medial and lateral compartments of the right (DMM) knee joint of Bortezomib and vehicle treated mice (d) Mean OARSI score in the medial and lateral compartments of the left non-operated (contralateral control) knee joint of Bortezomib and vehicle treated mice (e) Mean OARSI score in the medial and lateral compartments of the right (DMM) knee joint of Bortezomib and vehicle treated mice (f) Representative histology images of articular cartilage lesions (arrows) in the medial joint compartment. Data are presented as mean ± S.E.M (n = 8/group)

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