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Table 1 OKS and predicted utility scores (EQ-5D)a: used to model CRFA and IAS in primary analysis

From: Cooled radiofrequency ablation of the genicular nerves for chronic pain due to osteoarthritis of the knee: a cost-effectiveness analysis based on trial data

 

Baselineb

Month 1

Month 3

Month 6

Month 12

CRFA

IAS

CRFA

IAS

CRFA

IAS

CRFA

IAS

CRFA

IAS

OKS

Mean (SD)

16.7 (4.4)

16.9 (5.1)

33.3 (9.2)

29.4 (8.5)

34.6 (8.3)

24.6 (7.6)

35.7 (8.8)

22.4 (8.5)

34.3 (11.1)

22.0 (16.6)

 

Sample sizec

76

75

67

69

65

68

58

67

52

3

 

SE

0.50

0.59

1.13

1.03

1.02

0.93

1.16

1.04

1.54

9.61

Mapped EQ-5D

Mean (SE)

0.335 (0.029)

0.340 (0.030)

0.708 (0.033)

0.619 (0.031)

0.735 (0.032)

0.512 (0.030)

0.761 (0.035)

0.463 (0.032)

0.729 (0.042)

0.453 (0.238)

  1. Abbreviations: CRFA cooled radiofrequency ablation, IAS intra-articular steroid, OKS Oxford Knee Score, SD standard deviation, SE standard error
  2. aIncludes all available observations
  3. bTime points as per clinical trial NCT02343003
  4. cSample size represents subjects with available data at each time point. Based on full analysis set from clinical trial NCT02343003