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Table 1 OKS and predicted utility scores (EQ-5D)a: used to model CRFA and IAS in primary analysis

From: Cooled radiofrequency ablation of the genicular nerves for chronic pain due to osteoarthritis of the knee: a cost-effectiveness analysis based on trial data

  Baselineb Month 1 Month 3 Month 6 Month 12
CRFA IAS CRFA IAS CRFA IAS CRFA IAS CRFA IAS
OKS Mean (SD) 16.7 (4.4) 16.9 (5.1) 33.3 (9.2) 29.4 (8.5) 34.6 (8.3) 24.6 (7.6) 35.7 (8.8) 22.4 (8.5) 34.3 (11.1) 22.0 (16.6)
  Sample sizec 76 75 67 69 65 68 58 67 52 3
  SE 0.50 0.59 1.13 1.03 1.02 0.93 1.16 1.04 1.54 9.61
Mapped EQ-5D Mean (SE) 0.335 (0.029) 0.340 (0.030) 0.708 (0.033) 0.619 (0.031) 0.735 (0.032) 0.512 (0.030) 0.761 (0.035) 0.463 (0.032) 0.729 (0.042) 0.453 (0.238)
  1. Abbreviations: CRFA cooled radiofrequency ablation, IAS intra-articular steroid, OKS Oxford Knee Score, SD standard deviation, SE standard error
  2. aIncludes all available observations
  3. bTime points as per clinical trial NCT02343003
  4. cSample size represents subjects with available data at each time point. Based on full analysis set from clinical trial NCT02343003