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Table 1 Baseline characteristics of included patients

From: Efficacy and safety of tranexamic acid in geriatric hip fracture with hemiarthroplasty: a retrospective cohort study

Variable

TXA group

N = 289

Control group

N = 320

P

Age, yr

84.41 ± 7.38

85.21 ± 8.27

0.210

Gender, F/M

198/91

214/106

0.666

Height, cm

162.72 ± 9.49

162.47 ± 7.65

0.724

Weight, kg

60.82 ± 12.90

58.60 ± 12.02

0.058

BMI, kg/m2

24.12 ± 2.49

22.11 ± 3.85

0.155

Anesthesia, n (%)

 General

129 (44.64)

114 (35.63)

0.057

 CSE

79 (27.34)

110 (34.38)

 

 Spine

81 (28.03)

96 (30)

 

ASA rating, n (%)

 I

63 (21.80)

86 (26.88)

0.230

 II

116 (40.14)

107 (33.44)

 

 III

109 (37.72)

124 (38.75)

 

 IV

1 (0.34)

3 (0.93)

 

Comorbidities, n (%)

 0

24 (8.30)

47 (14.69)

0.074

 1

95 (32.87)

90 (28.13)

 

 2

112 (38.75)

121 (37.81)

 

 3

34 (11.76)

44 (13.75)

 

  ≥ 4

24 (8.30)

18 (5.63)

 

 Pre Hb level

123.02 ± 14.65

120.74 ± 15.94

0.068

 Pre Hct level

0.36 ± 0.04

0.35 ± 0.04

0.057

Anticoagulation therapy, n (%)

 Rivaroxaban

92 (31.83)

79 (24.69)

0.106

 LMWH

181 (62.63)

216 (67.5)

 

 None

16 (5.54)

25 (7.81)

 

Timing of initiation of VTE prophylaxis, n (%)

 Pre

159 (55.02)

180 (56.25)

0.068

  ≤ 12 h Post

105 (36.33)

94 (29.38)

 

  > 12 h Post

9 (3.11)

21 (6.56)

 

 None

16 (5.54)

25 (7.81)

 

 Pre ESA

156 (53.98)

183 (57.19)

0.426

 Cementless/Cement, n/n

200/89

220/100

0.904

 Operation time, min

88.19 ± 31.55

92.35 ± 49.16

0.220

 Intra-Crystalloid, ml

785.12 ± 117.83

1063.42 ± 063.4

0.329

 Intra-Colloid, ml

221.86 ± 195.85

312.00 ± 230.66

0.277

 PBV, ml

3849.19 ± 639.74

37,771.80 ± 652.23

0.141

Hospital level

 <1000 procedures/year

108 (37.37)

109 (34.06)

0.693

 1000–2000

109 (37.72)

128 (40.00)

 

 >2000

72 (24.91)

83 25.94()

 

Surgeon level

 <200 procedures/ year

75 (25.95)

104 (32.50)

0.197

 200–300

188 (65.05)

192 (60.00)

 

 >300

26 (9.00)

24 (7.50)

 
  1. Values are n (%) or mean ± SD
  2. BMI body mass index; CSE combined spine-epidural anesthesia, ASA American Society of Anesthesiologists, Hb Hemoglobin, Hct hematocrit, LMWH low-molecular-weight heparin, ESA erythropoiesis-stimulating agents, PBV patient blood volume, Post postoperative, Pre preoperative