Table 7 Mean T2 relaxation time and standard deviation of relaxation time for femur (median (IQR)) in the Full Analysis Set population
Mean T2 relaxation time (ms) | SD of relaxation time (ms) | ||||
|---|---|---|---|---|---|
Median (IQR) n = 38 | p-value | Median (IQR) n = 38 | p-value | ||
Whole Femur- whole layer | D180 vs D0 D360 vs D0 | −0.537 (−10.658; 2.368) − 1.595 (−9.338; 1.532) | 0.050 0.014 | −1.315 (−4.361; 2.227) − 0.588 (− 4.128; 1.634) | 0.160 0.279 |
Whole Femur- top layer | D180 vs D0 D360 vs D0 | − 1.589 (−6.682; 2.216) − 1.678 (− 6.797; 3.763) | 0.080 0.131 | − 0.697 (− 7.715; 5.048) 1.159 (− 5.690; 6.124) | 0.574 0.545 |
Whole Femur- middle layer | D180 vs D0 D360 vs D0 | −0.596 (10.378; 1.938) − 1.249 (− 10.187; 0.967) | 0.030 0.008 | −1.524 (− 5.920; 1.637) − 0.305 (− 5.309; 1.955) | 0.86 0.174 |
Whole Femur- bottom layer | D180 vs D0 D360 vs D0 | −0.259 (− 10.454; 3.226) − 2.051 (− 10.495; 1.684) | 0.094 0.009 | −0.944 (− 8.002; 1.725) − 0.402 (− 8.032; 1.057) | 0.027 0.055 |
Medial weight bearing femur- whole layer | D180 vs D0 D360 vs D0 | 0.318 (− 14.381; 3.036) − 1.680 (− 13.240; 2.583) | 0.198 0.147 | −1.320 (− 6.054; 2.027) − 0.585 (− 5.550; 1.085) | 0.059 0.124 |
Medial weight bearing femur- top layer | D180 vs D0 D360 vs D0 | −1.119 (− 8.54; 3.575) − 1.923 (− 7.076; 4.147) | 0.219 0.480 | 0.493 (−4.423; 3.233) − 1.741 (− 3.532; 10.667) | 0.782 0.717 |
Medial weight bearing femur- middle layer | D180 vs D0 D360 vs D0 | 0.115 (− 12.221; 2.005) − 1.725 (− 8.003; 0.934) | 0.086 0.057 | −1.335 (− 8.136; 1.699) − 1.718 (− 6.450; 0.685) | 0.037 0.050 |
Medial weight bearing femur- bottom layer | D180 vs D0 D360 vs D0 | −0.261 (− 13.971; 5.085) − 2.727 (− 10.766; 3.163) | 0.254 0.053 | −1.506 (− 11.723; 1.387) − 2.298 (− 8.391; 0.853) | 0.010 0.012 |
Lateral weight bearing femur- whole layer | D180 vs D0 D360 vs D0 | −3.129 (− 8.423; 1.453) − 1.748 (− 8.187; 2.160) | 0.011 0.032 | 0.179 (− 3.713; 2.078) − 0.123 (− 3.475; 2.057) | 0.613 0.613 |
Lateral weight bearing femur- top layer | D180 vs D0 D360 vs D0 | 0.580 (−7.286; 4.058) − 0.628 (− 6.597; 3.953) | 0.664 0.364 | −0.375 (− 11.374; 5.426) 0.897 (− 5.299; 6.409) | 0.412 0.792 |
Lateral weight bearing femur- middle layer | D180 vs D0 D360 vs D0 | −1.075 (− 7.777; 1.477) − 1.264 (− 9.870; 1.896) | 0.005 0.045 | 0.183 (− 3.536; 1.522) − 0.589 (− 3.179; 1.625) | 0.395 0.349 |
Lateral weight bearing femur- bottom layer | D180 vs D0 D360 vs D0 | −1.599 (− 12.514; 2.41) − 2.164 (− 10.944; 3.286) | 0.015 0.100 | −1.053 (− 5.959; 0.667) − 0.699 (− 6.740; 1.931) | 0.005 0.110 |