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Fig. 8 | BMC Musculoskeletal Disorders

Fig. 8

From: The effect of anti-IL-6 receptor antibody for the treatment of McH-lpr/lpr-RA1 mice that spontaneously developed destructive arthritis and enthesitis

Fig. 8

mRNA expression of Tnf, Il17 and Il6 genes. The expression levels of Tnf is significantly lower in MR16–1 treated group at week 16. The expression levels of Il17 is significantly lower in MR16–1 treated group at week 16. There is no significant difference of Il6 expression among both groups. Results are expressed as the mean ± standard error (n = 5 mice per group). Representative data are shown from three independent experiments with similar results. *p < 0.05, ***p < 0.001 by two-way ANOVA with Tukey’s multiple comparison test

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