The efficacy of liposomal bupivacaine compared with traditional peri-articular injection for pain control following total knee arthroplasty: an updated meta-analysis of randomized controlled trials

Table 1 The basic information of RCTs

		LB/traditional PAI
studies	country	cases	age	female	BMI	AN	EG	control group	follow-up	PA
alijanipour 2016	USA	59/59	64.3/64.9	30/32	32.3/28.7	SA	LB266mg	bupivacaine	6 weeks	Y
Bramlett 2012	USA	25/34	61.1/62.2	12.0/23	31.2/31.5	GA	LB266mg	bupivacaine	36 days	Y
collis 2016	USA	54/51	63.7/63.5	29/37	34.1/35.7	GA	LB266mg	ropivacaine, epinephrine, ketorolac, clonidine	8 weeks	N
declaire 2017	USA	47/49	69.7/67.7	26/28	31.5/31.9	SA/GA	LB266mg	ropivacaine, ketorolac, morphine, epinephrine	NM	Y
Jain 2016	USA	63/62	68.3/67.5	44/45	33.3/33.3	SA	LB266mg	bupivacaine, epinephrine, morphine	NM	Y
mont 2017	USA	70/69	66/66	43/39	32.4/31.3	SA	LB266mg	bupivacaine	NM	Y
schroer 2015	USA	58/53	67/68.6	34/32	32/32	SA/GA	LB266mg	bupivacaine	3 weeks	Y
Schumer 2018	USA	66/64	NM	NM	NM	SA	LB266mg	bupivacaine	6 weeks	N
schwarzkopf 2016	USA	20/18	63/59	13/8.0	29.3/29.5	SA	LB266mg	ropivacaine, clonidine, Toradol, Epinepherine	NM	Y
smith 2017	USA	104/96	66/66	50/68	31.5/31.6	SA	LB266mg	bupivacaine	6 weeks	N
Snyder 2016	USA	35/35	67.3/65.6	13/20	30.68/31.29	SA/GA	LB266mg	ropivacaine,epinephrine morphine, ketorolac	10 days	N
suarez 2018	USA	52/52	68.1/67.3	33/26	30.8/32.01	SA	LB266mg	bupivacaine,lidocaine epinephrine, morphine, ketorolac	6 weeks	Y
zlotnicki 2018	USA	38/40	63.2/64.3	19/26	35.5/35.4	SA/GA	LB266mg	bupivacaine	NM	N

AN anesthesia, SA spinal anesthesia, GA general anesthesia, NM not mentioned, PA power analysis

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