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Table 3 Multiple regression analysis

From: Association of serum bone- and muscle-derived factors with age, sex, body composition, and physical function in community-dwelling middle-aged and elderly adults: a cross-sectional study

model   B SE(B) β t 95% CI p R2
(a) Sclerostin as dependent variable
 1 Sexa 24.14 2.56 0.52 9.40 (19.08~29.20) < 0.001 0.267
 2 Sexa 23.13 2.50 0.49 9.24 (18.20~28.06) < 0.001 0.311
Age 0.58 0.14 0.21 4.04 (0.30~0.86) < 0.001  
 3 Sexa 19.71 2.72 0.42 7.23 (14.34~25.08) < 0.001 0.332
Age 0.71 0.14 0.26 4.80 (0.42~1.01) < 0.001  
SOS 0.15 0.05 0.17 2.92 (0.50~0.25) 0.004  
 4 Sexa 18.91 2.73 0.40 6.91 (13.52~24.29) < 0.001 0.342
Age 0.75 0.14 0.28 5.06 (0.46~1.05) < 0.001  
SOS 0.14 0.05 0.15 2.64 (0.03~0.24) 0.009  
TRACP5b −0.02 0.01 −0.11 −2.10 (−0.03~ − 0.001) 0.037  
(b) OC as dependent variable
 1 TRACP-5b 0.03 0.003 0.63 12.78 (0.03~0.04) < 0.001 0.404
 2 TRACP-5b 0.03 0.003 0.60 12.15 (0.03~0.04) < 0.001 0.428
Sexa −2.73 0.81 −0.16 −3.36 (−4.33~ − 1.13) 0.001  
 3 TRACP-5b 0.03 0.003 0.62 12.46 (0.03~0.04) < 0.001 0.438
Sexa −2.49 0.81 −0.15 −3.06 (−4.09~ − 0.89) 0.002  
Age −0.10 0.04 −0.11 −2.23 (−0.19~ − 0.01) 0.026  
(c) IGF-1 as dependent variable
 1 Age −1.03 0.22 −0.29 −4.68 (−1.47~ − 0.60) < 0.001 0.080
 2 Age −0.88 0.22 −0.24 −3.93 (−1.32~ − 0.42) < 0.001 0.107
SOS 0.21 0.07 0.17 2.85 (0.06~0.35) 0.005  
 3 Age −0.86 0.22 −0.24 −3.87 (−1.30~ − 0.42) < 0.001 0.124
SOS 0.19 0.07 0.16 2.60 (0.04~0.33) 0.010  
BMI 1.58 0.66 0.14 2.38 (0.27~2.89) 0.018  
  1. B, partial regression coefficient; SE, standard error; β, standardized partial regression coefficient; t, t-ratio; 95%CI, 95% confidence interval; p, p-value; R2, coefficient of determination
  2. BMI, body mass index; IGF-1, insulin-like growth factor-1; OC, osteocalcin; SMI, skeletal muscle mass index; SOS, speed of sound; TRACP-5b, tartrate-resistant acid phosphatase-5b
  3. Multiple regression analysis was performed with serum sclerostin, OC, and IGF-1 as dependent variables, and with age, gender, BMI, SOS, SMI, grip power, gait speed, and TRACP-5b as independent variables
  4. Selection of modelling was done using stepwise method
  5. a Women = 0, Men = 1