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Table 4 Prospective randomized controlled trials reported the effect of tourniquet pressure during total knee arthroplasty

From: Is lower tourniquet pressure during total knee arthroplasty effective? A prospective randomized controlled trial

Author (Year)

Country

Group [HTP] (N) vs. [LTP] (N)

Actual tourniquet pressure (mmHg)

Duration (min)

Release timing*

Anesthesia

Tourniquet failure

Effect of lower tourniquet pressure

Worland (1997) [14]

USA

[350 mmHg] (28) vs.

[SBP + 100 mmHg] (28)

350 vs. 230

23 vs. 22

Early

Spinal

NA

Provide bloodless operative field,

Less thigh pain

Clarke (2001) [12]

England

[SBP + 250 mmHg] (10) vs. [SBP + 125 mmHg] (11)

352 vs. 223

52–94 vs. 45–91

NA

General

0/10 (HTP) 1/11 (LTP)

Less postoperative wound hypoxia

Manén Berga (2002) [16]

Spain

[400 mmHg] (41) vs.

[SBP + 100 mmHg] (45)

400 vs. 260

77.4 vs. 73.7

Late

Spinal

2/45 (LTP)

Less postoperative pain, Provide bloodless operative field,

Fast recovery of ROM

Ishii (2005) [15]

Japan

[350 mmHg] (30) vs.

[SBP + 100 mmHg] (30)

350 vs. 238

50 vs. 48

Early

Spinal

NA

Provide bloodless operative field,

No difference in perioperative blood loss

Olivecrona (2012) [4]

Sweden

[SBP + adequate margin] (76) vs. [LOP + safety margin] (83)

252 vs. 246

87 vs. 87

NA

Spinal or General

3/159 (Total)

No postoperative infections and less wound complications in cuff pressure < 225 mmHg

Tuncali (2018) [27]

Turkey

[LOP + adequate margin] (46) vs. [estimated AOP + 20mHg] (47)

200 vs. 182

70 vs. 66

NA

Combined spinal epidural

0 (Total)

Excellent or good tourniquet performance in all patients,

No tourniquet related complications

The current study

Korea

HTP [SBP + 150 mmHg] (80) vs. LTP [SBP + 120 mmHg] (80)

255 vs. 234

83 vs. 82

Early (& reinflation)

Spinal

1/80 (HTP) 2/80 (LTP)

Provide bloodless operative field,

No difference in postoperative pain, thigh complication, VTE, and delayed rehabilitation

  1. *Timing of the tourniquet release was defined as one of two methods: late release (tourniquet was released after wound closure) or early release (tourniquet was released after implant fixation and before wound closure). In the current study, the tourniquet was released early after implant fixation for the arterial hemostasis and reinflated after hemostasis [20]
  2. HTP higher tourniquet pressure, LTP lower tourniquet pressure, RCT randomized controlled trial, SBP systolic blood pressure, LOP limb occlusion pressure, AOP arterial occlusion pressure, NA not applicable, ROM range of motion, HSS Hospital for Special Surgery, SLR straight leg raise, VTE venous thromboembolism