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Table 1 Baseline characteristics and change in physical function and in the anchors after 12–18 months

From: Minimal clinically important decline in physical function over one year: EPOSA study

  Baseline Change: 12–18 months follow-up - baseline P
Age, n, mean (SD), median (IQR), y 1886 73.8 ± 5.0 73 (70.77)     
Female Sex, n (%) 1886 977 (51.8)     
High education, n (%) 1886 1120 (58.8)     
Country, n (%) 1886       
 Italy   312 (16.8)     
 The Netherlands   407 (22.0)     
 Spain   413 (22.4)     
 Sweden   392 (23.0)     
 UK   362 (15.8)     
Clinical hand OA, n (%) 1886 1842 (16.7)     
Clinical hip/knee OA, n (%) 1886 1845 (22.6)     
AUSCAN for hand OAa, n, mean ± SD, median (IQR)
 Physical function 1842 9.1 ± 15.4 0 (0,11) 1842 1.1 ± 11.3 0 (0,4) <.0001
 Painc 1842 7.6 ± 15.2 0 (0,5) 1842 1.7 ± 14.4 0 (0,0) 0.1949
 Stiffness 1842 10.0 ± 18.7 0 (0,25) 1842 1.0 ± 17.2 0 (0,0) 0.1358
WOMAC for hip/knee OAa, n, mean ± SD, median (IQR)
 Physical function 1845 8.5 ± 13.2 2 (0,12) 1845 1.5 ± 11.3 0 (−1,4) 0.0123
 Pain 1845 10.0 ± 14.3 5 (0,15) 1845 1.4 ± 13.2 0 (−5,5) 0.2579
 Stiffness 1845 12.9 ± 18.6 0 (0,25) 1845 0.3 ± 17.9 0 (0,12) 0.0390
Grip strengthb, n, mean ± SD, median (IQR), kg 1862 27.7 ± 10.2 26 (20,35) 1826 −1.1 ± 5.8 −1 (−3.5,1.5) 0.0004
Walking-test timec, n, mean ± SD, median (IQR), sec 1854 3.3 ± 1.6 3 (2.3,3.8) 1830 0.1 ± 1.6 0 (−0.5,0.6) <.0001
HADS anxietyd, n, mean ± SD, median (IQR) 1886 4.5 ± 3.5 4 (2,7) 1872 −0.6 ± 2.6 −1 (−2,1) <.0001
HADS depressiond, n, mean ± SD, median (IQR) 1886 3.5 ± 3.0 3 (1,5) 1875 −0.3 ± 2.4 0 (−1,1) <.0001
EQ-5D-5 Le, n, mean ± SD, median (IQR) 1876 0.8 ± 0.2 0.8 (0.7,1.0) 1855 0.0 ± 0.2 0 (0.0,0.1) 0.0059
EQ VASf, n, mean ± SD, median (IQR) 1882 76.5 ± 16.2 80 (70,90) 1875 −0.5 ± 15.6 0 (−10,5) 0.0114
  1. Weighted data. Numbers of subjects, age, and sex were unweighted data. Except where indicated otherwise, values are the percent of subjects
  2. EPOSA European Project on OSteoArthritis, SD Standard deviation, IQR interquartile range, AUSCAN AUStralian/CANadian Osteoarthritis Hand Index, WOMAC Western Ontario and McMaster Universities Osteoarthritis Index, OA osteoarthritis, HADS Hospital Anxiety and Depression Scales, EQ-5D-5 L Health status using five dimensions, EQ VAS Health status using the visual analogue scale
  3. a Possible scores range from 0 to 100, with 100 indicating worse health status. b Lower values indicate worse performance. c Higher values indicate worse performance. d Possible scores range from 0 to 21, a score ≥ 8 indicates anxiety and/or depression. e Possible scores range from − 0.594 to 1, lower values indicating worse health status. f Possible scores range from 0 to 100, with 0 indicating worse health status
  4. The P are bold where they are less than or equal to the significance level cut-off of 0.05