Table 1 Cases of lower leg osteomyelitis caused by Actinomycosis reported in English language literature between 1990 and 2017 with our patient
Cases | Age/Gender | Location | Underlying disease | Culture result | Pathologic exam | Treatment | Outcome |
|---|---|---|---|---|---|---|---|
Atwaru et al. [9] | 32/M | Calcaneus | None | Primary: none Delayed: Actinomyces Israelii | Primary: none Delayed: Actinomyces | Antituberculosis medication → Penicillin (PO) 6 W | Total calcanectomy |
Lee et al. [15] | 59/M | Fibular | None | Actinomyces meyeri Fusobacterium nucleatum | Actinomyces | Fibular excision Ampicillin-sulbactam (IV) 3 W + Amoxicillin-clavulanate (PO) 8 W | Fibular excision |
Apotheloz et al. [5] | 47/M | Rt. lung Rt. Proximal tibia | Alcoholics smoking | Actinomyces meyeri | Actinomyces | Synovectomy Penicillin (IV) 8 W + penicillin (PO) 12 M | Cured |
Tekin et al. [20] | 90/F | Knee, ankle joint (proximal & distal tibia) | Unknown | Unknown | Actinomyces | Ampicillin/sulbactam (IV) 2 W + Amoxicillin-clavulanate (PO) 6 M | Lower leg amputation |
Kundu et al. [6] | 50/M | Knee joint (distal femur + proximal tibia) | Unknown | Actinomyces | Actinomyces | Repeated bone curettage Penicillin (IV) 6 W | Failed- amputation |
Nayak et.al. [17] | 30/M | Calcaneus | Unknown | Actinomyces MSSA | Actinomyces | Debridement/Antibead insertion ketaconazole + Tetracycline + Septran-DS (PO)6 W | Cured |
Yusof et al. [7] | 34/M | Knee joint, proximal tibia | Unknown | None | Actinomyces | Bactrim and amoxycillin (PO) 6 M | Cured, But ROM limitation |
Nandy et al. [21] | 52/M | Talus, medial malleolus | None | Unknown | Actinomyces | Clindamycin (IV) 3 W | Below knee amputation |
Our patient | 52/F | Distal femur | None | None | Actinomyces | Repeated bone curettage Penicillin (IV)8 W+ Amoxicillin-clavulanate (PO) 6 W | Cured |