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Table 2 Performance characteristics of ICD-9 based validation for musculoskeletal conditions against the ICPC Reference Standard

From: Identifying musculoskeletal conditions in electronic medical records: a prevalence and validation study using the Deliver Primary Healthcare Information (DELPHI) database

  Total TP TN FN FP Sensitivity [95 CI%] Specificity [95 CI%] PPV [95 CI%] NPV [95 CI%]
A. Analysis at Level of Patient
 All Ages 2493 998 1131 307 57 76.5 (74.1–78.8) 95.2 (93.8–96.4) 94.6 (93.1–95.8) 78.7 (77.0–80.3)
  0–17 253 43 194 16 0 72.9 (59.7–83.6) 100.0 (98.1–100.0) 100.0 (100.0–100.0) 92.4 (88.9–94.9)
  18–44 599 207 317 55 20 79.0 (73.6–83.8) 94.1 (91.0–96.3) 91.2 (87.1–94.1) 85.2 (82.0–88.0)
  45–64 951 442 370 115 24 79.4 (75.8–82.6) 93.9 (91.1–96.1) 94.9 (92.6–96.5) 76.3 (73.2–79.1)
  65+ 690 306 250 121 13 71.7 (67.1–75.9) 95.1 (91.7–97.3) 95.9 (93.3–97.6) 67.4 (63.9–70.7)
B. Analysis at Level of Encounter
 All Ages 21,964 2940 16,378 2220 426 57.0 (55.6–58.3) 97.5 (92.2–97.7) 87.3 (86.2–88.4) 88.1 (87.7–88.4)
  0–17 1133 55 1054 24 0 69.6 (58.3–79.5) 100.0 (99.7–100.0) 100.0 (100.0–100.0) 97.8 (96.9–98.4)
  18–44 4322 600 3316 314 92 65.6 (62.5–68.7) 97.3 (96.7–97.8) 86.7 (84.1–88.9) 91.3 (90.6–92.3)
  45–64 8688 1326 6214 961 187 58.0 (55.9–60.0) 97.1 (96.6–97.5) 87.6 (86.0–89.1) 86.6 (86.0–87.2)
  65+ 7821 959 5794 921 147 51.0 (48.7–53.3) 97.5 (97.1–97.9) 86.7 (85.7–88.5) 86.3 (85.7–86.8)
  1. TP True Positive, TN True Negative, FN False Negative, FP False Positive, CI Confidence Interval, PPV Positive Predictive Value, NPV Negative Predictive Value