Table 2 Inflammatory biomarkers in relationship to clinical features (cross sectional studies)
From: Inflammatory biomarkers in patients with sciatica: a systematic review
Study | Age (yr) | Duration (months) | Source | Technique | Marker | Clin O | Ass |
|---|---|---|---|---|---|---|---|
Piperno [16] | 40 + − 13 | 20 + −26 | serum | Degradation | PhosA2 | VAS | no |
Brisby [17] | N | 92 (5–390)a | serum CSF | ELISA | Il-8 | VAS | r = −0,48 |
Sugimor [18] | 26.4 (16–39) | N | serum | Latex agl | hsCRP | JOA | r = −0,583 |
Cheng [19] | 44 (30–72) | N | serum | ELISA | Il-17 | VAS | r = 0,458 |
Xue [20] | 52 (21–70) | N | serum NP Biopsy | mRNA qPCR | Il-21 | VAS | r = 0,809 |
Peng [21] | 34.2 (+ − 5.8)b | 4.5 (1–22) | serum | Western blot | CX3CL1 | VAS | r = 0, 393 |
serum | Western blot | CX3CL1 | JOA | r = − 0,342 | |||
serum | Western blot | CCL2 | VAS | r = 0, 360 | |||
serum | Western blot | CCL2 | JOA | r = −0,375 | |||
Palada [22] | 41.13 (15–65) | >  1 month | serum | mRNA qPCR | Il-6 | VAS | r = 0,380 |
CSF | mRNA qPCR | Il-8 | VAS | r = 0,395 | |||
serum | mRNA qPCR | MCP1 | VAS | r = 0,515 |