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Table 4 Adjusted HRs of vertebral fracture according to the duration of use of thiazides and loop diuretics

From: Association between diuretic use and the risk of vertebral fracture after stroke: a population-based retrospective cohort study

Duration of use

Thiazides

Loop diuretics

adjusted HRa

95% CI

p value

adjusted HRa

95% CI

p value

None

1 (ref.)

  

1 (ref.)

  

1–90 days

1.38

1.02–1.88

0.039

1.56

1.11–2.20

0.011

91–365 days

1.14

0.80–1.62

0.470

1.32

0.81–2.14

0.263

> 365 days

0.80

0.53–1.22

0.298

1.23

0.66–2.29

0.521

  1. aCalculated using a multivariate Cox proportional hazard regression model with adjustment for all baseline characteristics shown in Table 1
  2. Abbreviations: HR hazard ratio, CI confidence interval