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Table 4 Adjusted HRs of vertebral fracture according to the duration of use of thiazides and loop diuretics

From: Association between diuretic use and the risk of vertebral fracture after stroke: a population-based retrospective cohort study

Duration of use Thiazides Loop diuretics
adjusted HRa 95% CI p value adjusted HRa 95% CI p value
None 1 (ref.)    1 (ref.)   
1–90 days 1.38 1.02–1.88 0.039 1.56 1.11–2.20 0.011
91–365 days 1.14 0.80–1.62 0.470 1.32 0.81–2.14 0.263
> 365 days 0.80 0.53–1.22 0.298 1.23 0.66–2.29 0.521
  1. aCalculated using a multivariate Cox proportional hazard regression model with adjustment for all baseline characteristics shown in Table 1
  2. Abbreviations: HR hazard ratio, CI confidence interval