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Fig. 2 | BMC Musculoskeletal Disorders

Fig. 2

From: Investigating the effect of proteoglycan 4 on hyaluronan solution properties using confocal fluorescence recovery after photobleaching

Fig. 2

Tracer diffusion coefficients of FITC-dextran (2000 kDa) through 1500 kDa HA solutions ±450 μg/ml PRG4 (▪ for HA+ PRG4, for HA) (a), 500 kDa HA solutions ±450 μg/ml PRG4 (b); 1500 kDa HA solutions ±45 μg/ml PRG4 (c), 500 kDa HA solutions ±45 μg/ml PRG4 (d). Data points are fit to the universal scaling equation (dashed lines = HA + PRG4, solid lines = HA). For both 1500 and 500 kDa HA (a, b), the diffusion of the tracer was significantly affected by HA concentration (both p < 0.01) and the presence of 450 μg/ml PRG4 (both p < 0.05), with no interaction effect (p = 0.78 and 0.85 respectively). For both 1500 and 500 kDa HA (c, d), the diffusion of the tracer was significantly affected by HA concentration (both p < 0.01) and the presence 45 μg/ml PRG4 (p < 0.01 and p < 0.05, respectively), with no interaction effect detected (p = 0.18 and 0.646 respectively)

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