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Fig. 5 | BMC Musculoskeletal Disorders

Fig. 5

From: The commercial pig as a model of spontaneously-occurring osteoarthritis

Fig. 5

a Proliferation of osteoblasts obtained from non-damaged adult and damaged older adult pig joints measured over a 14 day time period by MTS assay. Data points represent the mean cell number ± SEM (n = 3). b Representative light microscope images of alizarin red stained osteoblasts isolated from non-damaged adult and damaged older adult joints. c ALP activity isolated from non-damaged adult (n = 3 animals) and damaged older adult joints (n = 3 animals). Values represent mean ALP activity ± SEM. d Maximal mitochondrial ATP production in osteoblasts obtained from adult (n = 3 non-damaged; n = 3 damaged) and older adult (n = 3 non-damaged; n = 3 damaged) pig joints. ** = p < 0.01. Bars represent mean ± SEM. e Citrate synthase activity in osteoblasts obtained from adult (n = 3 non-damaged; n = 3 damaged) and older adult (n = 3 non-damaged; n = 3 damaged) pig joints. Bars represent mean ± SEM. ** = p < 0.01, *** = p < 0.001

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