Table 4 Hazard ratios for rheumatoid arthritis phenotypes according to dichotomized cumulative average total fish intake in the Nurses’ Health Study and Nurses’ Health Study II (n = 166,013)

 Cases/person-years

53/185,861

1027/3,678,049

 Age-adjusted model^a

1.00 (Ref)

0.84 (0.64–1.11)

0.23

 Multivariable model^b

1.00 (Ref)

0.85 (0.64–1.13)

0.27

 Cases/person-years

34/185,640

638/3,670,434

 Age-adjusted model^a

1.00 (Ref)

0.84 (0.59–1.20)

0.34

 Multivariable model^b

1.00 (Ref)

0.86 (0.60–1.22)

0.39

 Cases/person-years

19/185,340

389/3,668,519

 Age-adjusted model^a

1.00 (Ref)

0.84 (0.53–1.34)

0.47

 Multivariable model^b

1.00 (Ref)

0.85 (0.53–1.35)

0.48

 Cases/person-years

37/134,613

454/2,057,424

 Age-adjusted model^a

1.00 (Ref)

0.71 (0.50–1.00)

0.048

 Multivariable model^b

1.00 (Ref)

0.73 (0.52–1.02)

0.066

 Cases/person-years

22/134,452

302/2,053,251

 Age-adjusted model^a

1.00 (Ref)

0.83 (0.53–1.29)

0.40

 Multivariable model^b

1.00 (Ref)

0.85 (0.55–1.32)

0.47

 Cases/person-years

15/134,186

152/2,051,358

 Age-adjusted model^a

1.00 (Ref)

0.54 (0.31–0.92)

0.024

 Multivariable model^b

1.00 (Ref)

0.55 (0.32–0.94)

0.029

 Cases/person-years

16/52,659

573/1,645,311

 Age-adjusted model^a

1.00 (Ref)

1.13 (0.69–1.87)

0.62

 Multivariable model^b

1.00 (Ref)

1.14 (0.69–1.88)

0.60