Table 3 Time varying variables

EQ-5D

Visual Analogue Scale (0–100; higher score is better)

69.2 (17.7)

78.3 (15)

78.2 (14.5)

EQ-5D utility

Utility score (−0.148 to 1; higher positive score is better)

0.59 (0.21)

0.82 (0.14)

0.82 (0.14)

SF-12

Physical Composite Scale (PCS) Score (0–100; higher score is better)

34.3 (7.5)

43.2 (12.6)

44.9 (9.2)

Mental Health Composite Scale (MCS) Score (0–100; higher score is better)

51.6 (10.7)

54.0 (8.8)

54.0 (8.7)

WOMAC

Pain (0–20; higher score, more pain)

10.1 (3.6)

3.4 (3.0)

2.9 (3.2)

Stiffness (0–8; higher score, more stiffness)

4.2 (1.7)

2.1 (1.6)

1.7 (1.5)

Physical Function (0–68; higher score, more limitations)

33.8 (11.9)

13.2 (11.2)

12.4 (11.5)

HADS

Anxiety (0–21; higher score, more anxiety)

5.6 (3.9)

4.0 (3.4)

4.1 (3.6)

Depression (0–21; higher score, more depression)

4.8 (3.3)

3.1 (3.2)

3.3 (3.1)

SLANSS

Neuropathic pain (0–24; score > =12, pain of neuropathic origin)

7.0 (6.6)

6.4 (6.9)

5.7 (6.4)