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Table 3 Effectiveness In Head To Head Trials Comparing Biologic with Combination DMARD Strategies Assessed By Random Risk Ratio and Heterogeneity

From: Intensive therapy and remissions in rheumatoid arthritis: a systematic review

 

Trials

Random Risk Ratio (95% CI)

Heterogeneity

All

6

1.06 (0.93, 1.21)

I2 = 21%

Early

4

1.05 (0.88, 1.24)

I2 = 40%

Established

2

1.21 (0.88, 1.68)

I2 = 0%

Established First 6 Months

2

1.74 (1.14, 2.64)

I2 = 0%