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Fig. 3 | BMC Musculoskeletal Disorders

Fig. 3

From: The hsa-miR-181a-5p reduces oxidation resistance by controlling SECISBP2 in osteoarthritis

Fig. 3

Transfection of miR-181a-5p affects the phenotype and oxidation resistance of chondrocytes through SBP2. a The expression of hsa-miR-181a-5p, COL2A1, ACAN and MMP13 after transfection with mimic-181a-5p for 24 h in SW1353 cells. (n = 3, 3). b The expression of hsa-miR-181a-5p, COL2A1, ACAN and MMP13 after transfection with inhibitor-181a-5p for 24 h in SW1353 cells. (n = 3, 3). c The expression of SBP2 after transfection with mimic-181a-5p or inhibitor-181a-5p for 24 h in SW1353 cells. (n = 3, 3). d The expression of SBP2 after transfection with mimic-181a-5p or inhibitor-181a-5p for 24 h in SW1353 cells. e Total GPXs activity after transfection with mimic-181a-5p or inhibitor-181a-5p for 24 h in SW1353 cells. (n = 3, 3). f The expression of mmu-miR-181a-5p, Sbp2 and SBP2 following ITS treatment in ATDC5 cells. (n = 3, 3). The data are expressed as the mean ± SEM; *, ** and *** indicate P < 0.05, 0.01 and 0.001, respectively

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