Fig. 2
From: The hsa-miR-181a-5p reduces oxidation resistance by controlling SECISBP2 in osteoarthritis
SBP2 regulates the biosynthesis of three selenoproteins and oxidation resistance in chondrocytes. a The expression of total (endogenous and exogenous) mSBP2 after transfection with pEGFP-N1-mSBP2 for 24 h in SW1353 cells. (n = 3, 3). b The expression of endogenous and exogenous SBP2 after transfection with pEGFP-N1-mSBP2 for 24 h in SW1353 cells. c The expression of SBP2, GPX1, GPX4 and SELS after transfection with 2 μg of pEGFP-N1-mSBP2 for 24 h in SW1353 cells. (n = 3, 3). d The expression of SBP2, GPX1, GPX4 and SELS after transfection with si-SBP2 for 24 h in SW1353 cells. (n = 3, 3). e Total GPXs activity after transfection with pEGFP-N1-mSBP2 or si-SBP2 for 24 h in SW1353 cells. (n = 3, 3). The data are expressed as the mean ± SEM; *, ** and *** indicate P < 0.05, 0.01 and 0.001, respectively