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Table 3 Bone shape mode and sex, incident knee ROA

From: Bone shape mediates the relationship between sex and incident knee osteoarthritis

Mode Association of mode and incident knee ROA Mode among knees without incident ROA, by gender
OR (95% C.I.)* p-value Men Mean (SD) Women Mean (SD)
tibia, mode 1 1.12(0.97,1.29) 0.130 −0.06 (0.93) −0.11 (1.02)
tibia, mode 2 1.18(1.03,1.37) 0.021 0.20 (1.00) −0.23 (0.94)**
tibia, mode 3 0.99(0.87,1.13) 0.868 −0.25 (1.05) 0.22 (0.92)**
tibia, mode 4 0.95(0.83,1.09) 0.496 0.001 (0.93) −0.03 (1.00)
tibia, mode 5 1.12(0.97,1.28) 0.117 0.02 (0.94) −0.13 (0.97)
tibia, mode 6 0.94(0.82,1.08) 0.400 −0.07 (1.06) 0.05 (0.91)
tibia, mode 7 1.06(0.92,1.22) 0.445 −0.17 (1.05) 0.03 (0.93)
tibia, mode 8 0.94(0.82,1.08) 0.387 0.30 (0.89) −0.13 (0.07)**
tibia, mode 9 1.15(1.00,1.32) 0.042 −0.06 (1.11) −0.09 (1.00)
tibia, mode 10 0.79(0.67,0.93) 0.006 −0.21 (0.98) 0.25 (0.98)**
tibia, mode 11 1.04(0.90,1.19) 0.598 0.27 (1.03) −0.20 (0.91)**
tibia, mode 12 0.86(0.75,0.99) 0.031 −0.004 (1.08) 0.06 (1.04)
tibia, mode 13 0.94(0.82,1.08) 0.381 0.05 (1.01) 0.09 (1.02)
femur, mode 1 1.05(0.90,1.21) 0.552 −0.54 (0.92) 0.30 (0.91)**
femur, mode 2 1.00(0.88,1.15) 0.943 −0.04 (0.86) 0.10 (0.95)
femur, mode 3 1.11(0.96,1.29) 0.170 −0.13 (1.01) −0.07 (1.02)
femur, mode 4 0.85(0.73,0.98) 0.025 −0.21 (1.00) 0.30 (0.89)**
femur, mode 5 0.95(0.83,1.09) 0.468 0.16 (0.95) −0.12 (0.91)**
femur, mode 6 1.11(0.97,1.27) 0.147 −0.15 (1.00) 0.02 (0.95)
femur, mode 7 1.01(0.88,1.15) 0.912 0.08 (0.98) −0.08 (1.01)
femur, mode 8 0.93(0.81,1.08) 0.339 −0.21 (1.01) 0.10 (0.95)**
femur, mode 9 1.01(0.88,1.16) 0.899 0.11 (0.97) 0.02 (0.96)
femur, mode 10 0.81(0.70,0.94) 0.005 −0.09 (0.98) 0.21 (0.95)
femur, mode 11 0.93(0.81,1.06) 0.276 0.04 (0.91) 0.01 (1.01)
femur, mode 12 0.95(0.83,1.08) 0.423 −0.12 (0.83) 0.14 (0.98)**
femur, mode 13 0.94(0.81,1.09) 0.380 0.14 (1.01) −0.08 (0.90)**
  1. Total effect of sex (women vs. men): OR (95% CI)*= 1.49 (1.04, 2.12)
  2. *Adjusting for age, BMI, race, clinic site, knee injury and surgery
  3. **p-value < 0.05