Author | Diagnose | No. Of patients | Age (years) | Interventions | Drainage | Tourniquet | Transfusion criteria | DVT prophylaxis | DVT screen |
---|---|---|---|---|---|---|---|---|---|
Huang [16] | OA | VI: 92 | VI: 64.7 | VI: 3 g used before inflation | Yes | Yes | 70 g/L ≤ Hb ≤ 90 g/L with anemia, Hb ≤70 g/L | LMWH Rivaroxaban | Ultrasound |
 | Combined: 92 | Combined: 65.4 | Combined:1.5 g used intravenously before inflation + 1.5 g used topically |  |  |  |  |  | |
Jain [17] | OA | VI:60 | VI: 70.0 | VI: 15 mg/kg 30 min before skin incision, 10 mg/kg was repeated 3 and 6 h later. | No | No | 7.0 g/d L ≤ Hb ≤ 8.0 g/dL with symptomatic anemia or Hb ≤7.0 g/dL | Aspirin | Clinical+ ultrasound |
 | Combined:59 | Combined: 68.27 | Combined: Same IV dose + 2 g used before closure of arthrotomy |  |  |  |  |  | |
Nielsen[22] | NS | VI:30 | VI: 63.2 | VI: 1 g used + 100 mL of saline used after closure of the capsule | No | No | Hb < 7.5 g/dL or < 10 g/dL with heart disease or Hb reduced > 25% | Rivaroxaban | Clinical |
 | Combined:30 | Combined: 65.5 | Combined: same IV dose+ 3 g used after closure of the capsule |  |  |  |  |  | |
Lee [23] | OA | VI:93 | VI: 73.4 | VI: 10 mg/kg 30 min before deflation, same dose repeated 3 h later | Yes | Yes | 7.0 g/dL ≤ Hb ≤ 8.0 g/dL with symptomatic anemia or Hb ≤7.0 g/dL | Rivaroxaban, Aspirin | Clinical +CT |
 | Combined:95 | Combined: 72.1 | Combined: 10 mg/kg 30 min before deflation, same dose repeated 3 h later + 2 g injected. |  |  |  |  |  | |
Song [24] | OA | VI:50 | VI: 69.2 | VI: 10 mg/kg 20 min before inflation,10 mg/kg 15 min before deflation, and 10 mg/kg 3 h later. | Yes | Yes | Hb < 8 g/% | LMWH | Ultrasound + CT |
 | Combined:50 | Combined: 70.8 | Combined: Same IV dose + 1.5 g used topically after wound closure |  |  |  |  |  | |
Liu [19] | OA | VI:25 | VI: NS | VI: 1 g 10 min before inflation | Yes | Yes | Hb ≤8 g/dL | Rivaroxaban | Ultrasound |
 | Combined:25 | Combined: NS | Combined: same VI dose + 1 g 10 min before inflation |  |  |  |  |  |