Fig. 2
From: Age-dependent bone loss and recovery during hindlimb unloading and subsequent reloading in rats
Distal Femoral Metaphysis μCT results. Representative regions of interest of trabecular bone for Adult (left) and Aged (right) femurs at baseline. Adult rats exhibited greater BV/TV, Tb.N, and reduced Tb.Sp than Aged rats. 14 days of hindlimb unloading resulted in significant loss of trabecular bone in Adult rats, but no significant decrease in Aged rats. By day 3 of reloading, Adult rats had recovered trabecular bone volume, while Aged rats exhibited continued loss of bone. Brackets indicate significant differences between groups (p < 0.05). Asterisks (*) indicate a main effect of age in a parameter between Adult and Aged animals (p < 0.05)