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Table 3 The treatments in four cases of tertiary and congenital syphilis with syphilitic hip arthritis

From: The disappearance of femoral head and neck resulting from extensive bone defect caused by secondary syphilis: a case report and literature review

Authors

Stage of syphilis

Publication year

Lesion sites

Lesion depth

Medical treatment

Surgical treatment

Spyridonidis et al. [34]

Tertiary syphilis

2002

Left hip joint

Osteolysis and periosteal reaction

Intravenous penicillin G (16 million units per day) for 5 days; intramuscular benzyl-penicillin (2.4 million units a week) for 3 weeks

None

Brain et al. [58]

Congenital syphilis

1926

Both hip joints

Erosion at the inner end of the epiphyseal line of the femur

Not given

Not given

Coblentz et al. [59]

Congenital syphilis

1970

Right hip joint

Destructive metaphysitis

Not given

Not given

Greenall et al. [60]

Congenital syphilis

2010

Both hip joints

Metaphysitis and bony destructive changes

Benzylpenicillin and Cefotaxime

None