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Table 6 Sensitivity analyses: doubling doses based on the pooled analyses

From: Dose-response relationship between cumulative physical workload and osteoarthritis of the hip – a meta-analysis applying an external reference population for exposure assignment

Assigned exposure parameters

Sensitivity analysis

Pooled OR (95% CI)

Doubling dosea

a. cumulative tons of weights ≥20 kg handled

1

2.09 (95% CI 1.40–3.10) for appr. the 90th percentile of the studies included by Bergmann et al. [2]

6100 tons

2

2.15 per 10,000 tons (95% CI 1.39–3.34)

9000 tons

3

1.64 per 10,000 tons (95% CI 1.13–2.40)

14,000 tons

b. cumulative tons of weights ≥20 kg handled > 10 times/day

1

2.09 (95% CI 1.40–3.10) for appr. the 90th percentile of the studies included by Bergmann et al. [2]

6000 tons

2

2.24 per 10,000 tons (95% CI 1.42–3.54)

8600 tons

3

1.94 per 10,000 tons (95% CI 1.20–3.14)

10,500 tons

c. cumulative number [×  1000] of lifting and/or carrying operations of weights ≥20 kg

1

2.09 (95% CI 1.40–3.10) for appr. the 90th percentile of the studies included by Bergmann et al. [2]

218,000

2

11.86 per 106 handlings (95% CI 2.99–47.06)

280,300

3

3.85 per 106 handlings (95% CI 1.39–10.70)

514,000

  1. a calculated with the exact pooled OR and rounded down to hundred