TY - JOUR AU - Antoniou, Tony AU - Macdonald, Erin M. AU - Yao, Zhan AU - Gomes, Tara AU - Tadrous, Mina AU - Ho, Joanne M.-W. AU - Mamdani, Muhammad M. AU - Juurlink, David N. AU - for the Canadian Drug Safety and Effectiveness Research Network PY - 2018 DA - 2018/05/22 TI - A population-based study of the risk of osteoporosis and fracture with dutasteride and finasteride JO - BMC Musculoskeletal Disorders SP - 160 VL - 19 IS - 1 AB - Dutasteride is a potent inhibitor of 5-alpha reductase enzymes that reduces concentrations of dihydrotestosterone to a greater extent than finasteride. Whether this has adverse implications for bone health is unknown. We compared the risk of osteoporosis and fractures in older men treated with dutasteride or finasteride. SN - 1471-2474 UR - https://doi.org/10.1186/s12891-018-2076-9 DO - 10.1186/s12891-018-2076-9 ID - Antoniou2018 ER -