A study of the factors associated with cervical spinal disc degeneration, with a focus on bone metabolism and amino acids, in the Japanese population: a cross sectional study

Wada, Kanichiro; Tanaka, Toshihiro; Kumagai, Gentaro; Kudo, Hitoshi; Asari, Toru; Chiba, Daisuke; Ota, Seiya; Kamei, Keita; Takeda, On; Nakaji, Shigeyuki; Ishibashi, Yasuyuki

doi:10.1186/s12891-018-2055-1

Table 3 Spearman correlation of parameters in 193 women

From: A study of the factors associated with cervical spinal disc degeneration, with a focus on bone metabolism and amino acids, in the Japanese population: a cross sectional study

Caracterics	Minimum % A/P diameter	Sevierity score of CDD	BMI	SMI	TMS in flexion	TMS in extention	Exercise habit	T score of BMD	BAP	NTX	TRACP-5b	total P1NP	25(OH)D3	Pent	Thr	Trp	Val	His	Phe	Met	Ile	Lys	Leu
Age	-.516^**	.683^**	.266^**	.227^**	-.432^**	-.171^*	.179^*	-.776^**	.455^**	.305^**	.585^**	.196**	.507^**	.542^**	−.127	-.221^**	−.016	−.019	.139	−.059	−.127	.254^**	−.127
Minimum % A/P diameter		-.527^**	-.226^**	-.173^*	.208^**	−.011	−.048	.411^**	-.364^**	-.214^**	-.358^**	-.190^**	-.280^**	-.233^**	.061	.099	−.086	−.043	−.075	−.002	−.011	-.162^*	−.021
Sevierity score of CDD			.287^**	.243**	-.268^**	−.059	.005	-.533^**	.399^**	.227^**	.470^**	.253^**	.342^**	.345^**	−.065	−.091	.039	.009	.080	−.070	−.109	.322^**	−.056
BMI				.800^**	−.097	.011	.072	-.210^**	.184^*	.101	.092	.069	.176^*	−.141	.153^*	.011	.248^**	.145^*	.137	.011	.177^*	.129	.144^*
SMI					−.085	.041	.031	−.124	.161^*	.048	.114	.090	.172^*	−.114	.161^*	−.063	.172^*	.141	.145^*	.081	.115	.124	.143^*
TMS in flexion						.458^**	.035	.344^**	-.191^*	-.174^*	-.240^**	.029	-.193^*	-.287^**	.054	.112	.074	.114	.026	.071	.033	−.090	.120
TMS in extention							.098	.178^*	−.006	−.028	−.037	.058	−.009	-.188^*	.075	.109	.150	.103	.047	.026	.039	−.026	.158^*
Exercise habit								-.145^*	.033	−.013	.022	−.046	.143^*	.096	−.044	−.120	.066	.038	−.002	−.061	.024	−.016	.050
T score of BMD									-.547^**	-.412^**	-.586^**	-.348^**	-.419^**	-.372^**	.057	.153^*	−.041	.069	−.115	.011	.035	-.261^**	.068
BAP										.535^**	.777^**	.713^**	.255^**	.130	−.067	.017	.106	.040	.116	.058	.075	.267^**	.090
NTX											.679^**	.576^**	.124	.143^*	.032	−.068	−.002	.043	.118	.039	.061	.205^**	.023
TRACP-5b												.697^**	.342**	.327^**	−.002	−.076	−.018	−.014	.065	.030	−.048	.290^**	−.028
total P1NP													.083	.038	.035	−.010	.081	.002	.055	.057	.052	.229^**	.074
25(OH)D3														.410^**	−.073	−.082	.055	.144^*	.087	−.024	−.104	.245^**	−.005
Pent															-.190^**	−.139	-.227^**	.012	.130	−.037	-.201^**	.101	-.221^**
Thr																.198^**	.194^**	.377^**	.118	.609^**	.203^**	.467^**	.179^*
Trp																	.408^**	.278^**	.244^**	.337^**	.355^**	.233^**	.420^**
Val																		.238^**	.282^**	.264^**	.768^**	.287^**	.866^**
His																			.332^**	.444^**	.214^**	.473^**	.413^**
Phe																				.484^**	.329^**	.279^**	.382^**
Met																					.380^**	.480^**	.369^**
Ile																						.176^*	.819^**
Lys																							.297^**
Leu

*p < 0.05, **P < 0.0001
Abbreviations: A/P anterior-posterior, Sevierity score of CDD severity score of cervical disc degeneration from C3/4 to C7/T1, BMI body mass index, SMI Skeletal muscle mass index, TMS trunk muscle strength, BMD bone mineral density, BAP bone-specific alkaline phosphatase, NTX cross-linked N-telopeptide of type 1 collagen, TRACP-5b bone tartrate-resistant acid phosphatase-5b, total P1NP total type 1 procollagen N-terminal propeptide, Pent pentosidine, Thr threonine, Trp tryptophan, Val valine, His histidine, Phe phenylalanine, Met methionine, Ile isoleuicine, Lys lysine, Leu leucine

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ISSN: 1471-2474

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