Variable | Oral TXA Group | IA TXA Group | P value |
---|---|---|---|
Primary outcome | |||
 Total blood loss (mL)b | 788.8 ± 349.1 | 872.4 ± 393.1 | 0.21 |
Secondary outcomes | |||
 Intro-operative blood loss (mL)b | 143.1 ± 25.4 | 145.6 ± 28.7 | 0.58 |
 Postop. IV fluid amount (mL)b | 2729.9 ± 366.5 | 2818.1 ± 419.2 | 0.18 |
 Blood transfusion (U)a | 7 | 9 | 0.73 |
 Transfusion rate (%)a | 3 (4%) | 4 (5%) | 0.69 |
 Postop. laboratory values at 72 hb | |||
  Hemoglobin (g/dL) | 11.2 ± 1.3 | 10.9 ± 1.2 | 0.22 |
  Reduction of hemoglobin (g/dL) | 2.2 ± 0.9 | 2.4 ± 1.1 | 0.66 |
  Hematocrit (L/L) | 0.34 ± 0.04 | 0.32 ± 0.03 | 0.20 |
  Red blood cell count (·×1012/L) | 3.6 ± 0.4 | 3.5 ± 0.4 | 0.37 |
  Platelet count (×109/L) | 165.8 ± 53.2 | 162.2 ± 57.7 | 0.70 |
  Prothrombin time (s) | 11.7 ± 1.3 | 12.0 ± 1.3 | 0.17 |
  INR | 0.9 ± 0.1 | 0.9 ± 0.6 | 0.76 |
  APTT (s) | 30.8 ± 5.0 | 31.4 ± 3.8 | 0.38 |
  Fibrinogen (g/L) | 4.5 ± 1.0 | 4.4 ± 1.3 | 0.67 |
  D-Dimer (mg/L) | 3.4 ± 2.2 | 3.2 ± 1.9 | 0.60 |
  FDP (mg/L) | 9.2 ± 6.4 | 9.1 ± 8.0 | 0.96 |