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Table 2 Multivariable linear regression result of associations between cytokines and age, gender, K/L grade and affected joint (e.g. knee vs. hip)

From: Serum and synovial fluid cytokine profiling in hip osteoarthritis: distinct from knee osteoarthritis and correlated with pain

Cytokines Covariates Sig. 95% CI
Lower Upper
EGF Age 0.396 −1.440 0.573
Gender 0.177 −34.025 6.343
K/L Grade 0.437 −7.964 18.331
Affected Joint* < 0.001 −37.895 −14.098
FGF2 Age 0.370 −1.761 0.659
Gender 0.195 −40.270 8.269
K/L Grade 0.803 −13.809 17.809
Affected Joint * 0.003 −36.048 −7.434
MCP3 Age 0.778 −0.751 1.001
Gender 0.238 −28.085 7.046
K/L Grade 0.909 −12.108 10.776
Affected Joint * 0.005 −25.219 −4.508
MIP1α Age 0.863 −1.426 1.197
Gender 0.298 −40.207 12.400
K/L Grade 0.572 −22.039 12.228
Affected Joint 0.130 −3.555 27.458
IL8 Age 0.799 −0.881 0.680
Gender 0.544 −20.479 10.832
K/L Grade 0.731 −8.422 11.973
Affected Joint * 0.049 −18.501 −0.042
  1. *p < 0.05