Serum and synovial fluid cytokine profiling in hip osteoarthritis: distinct from knee osteoarthritis and correlated with pain

Table 2 Multivariable linear regression result of associations between cytokines and age, gender, K/L grade and affected joint (e.g. knee vs. hip)

Cytokines	Covariates	Sig.	95% CI
Cytokines	Covariates	Sig.	Lower	Upper
EGF	Age	0.396	−1.440	0.573
	Gender	0.177	−34.025	6.343
	K/L Grade	0.437	−7.964	18.331
	Affected Joint*	< 0.001	−37.895	−14.098
FGF2	Age	0.370	−1.761	0.659
	Gender	0.195	−40.270	8.269
	K/L Grade	0.803	−13.809	17.809
	Affected Joint *	0.003	−36.048	−7.434
MCP3	Age	0.778	−0.751	1.001
	Gender	0.238	−28.085	7.046
	K/L Grade	0.909	−12.108	10.776
	Affected Joint *	0.005	−25.219	−4.508
MIP1α	Age	0.863	−1.426	1.197
	Gender	0.298	−40.207	12.400
	K/L Grade	0.572	−22.039	12.228
	Affected Joint	0.130	−3.555	27.458
IL8	Age	0.799	−0.881	0.680
	Gender	0.544	−20.479	10.832
	K/L Grade	0.731	−8.422	11.973
	Affected Joint *	0.049	−18.501	−0.042

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