Table 2 Prevalence of self-reported symptoms related to sleep-disturbances and sleep apnea among the respondents in the Osteogenesis imperfecta patient cohort and controls
Number of patients with symptoms (%) N = 56 | Number of controls with symptoms (%) N = 56 | Significance of difference between the study groups (Chi-Square test) | |
|---|---|---|---|
Snoring | 32/52 (62) | 15/54 (28) | 11.1 p = 0.001 |
Pauses of breathing during sleep | 13/42 (31) | 3/54 (6) | 9.9 p = 0.002 |
Restless sleep | 43/55 (78) | 23/54 (43) | 12.9 p < 0.001 |
Grinding of teeth during sleep | 22/52 (42) | 23/55 (42) | Non-significant |
Recurrent nightmares | 16/50 (32) | 2/55 (4) | 13.3 p < 0.001 |
Daytime sleepiness | 43/53 (81) | 34/56 (61) | 5.6 p = 0.018 |
Likelihood of dozing | 14/52 (27) | 5/56 (9) | 6.3 p = 0.012 |
Dysphagia | 17/51 (33) | 1/55(2) | 20.0 p < 0.001 |
Difficulties of concentration | 24/50 (48) | 6/54 (11) | 16.6 p < 0.001 |
Nocturia | 15/51 (29) | 5/54 (9) | 5.8 p = 0.016 |
Restless legs | 19/51 (37) | 8/54 (15) | 10.0 p = 0.002 |
Diagnosed sleep apnea | 8/54 (15) | 1/55 (2) | 5.4 p = 0.020 |