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Table 1 Characteristics of individual studies

From: TRAIL gene 1595C/T polymorphisms contribute to the susceptibility and severity of intervertebral disc degeneration: a data synthesis

Authors Year Country Ethnicity Gender (M/F)   Age, mean (SD)   Matching Control source Genotyping method IDD diagnosis IDD severity standard Study quality
     Case Control Case Control       
Zhang [10] 2015 China Han Chinese 198/114 121/75 49.54(8.87) 48.65(8.12) Age and gender Healthy subjects PCR-RFLP Symptoms, MRI Schneiderman’s classification 11
Du [8] 2015 China Han Chinese 73/80 62/69 40.2(5.1) 38.6(5.0) Age and gender Healthy subjects PCR-RFLP Symptoms, MRI Schneiderman’s classification 11
Xu [9] 2015 China Han Chinese 54/46 58/42 59 49 Age and gender Healthy subjects PCR- RFLP Symptoms, MRI Schneiderman’s classification 10
  1. M male, F female, SD standard deviation, IDD intervertebral disc degeneration, PCR-RFLP polymerase chain reaction–restriction fragment length polymorphism, MRI magnetic resonance imaging