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Fig. 1 | BMC Musculoskeletal Disorders

Fig. 1

From: Micro-structural bone changes in early rheumatoid arthritis persist over 1-year despite use of disease modifying anti-rheumatic drug therapy

Fig. 1

a 150 mm Scout View Image. Dots = Reference points for the distal radial (medial distal cortex radius) and metacarpal head (distal tip of most proximal MH) scans. Larger shaded boxes = Distal Radius (110 slices) and Metacarpal (220 slices) scan lengths. Smaller boxes with UUD, MH2 and MH3 text = Three Regions of Interests (ROIs) evaluated (UUD = Ultra-ultra distal, MH = Metacarpal head 2 or 3). b Single HR-pQCT image slices of a cross-sectional image of MH (Top) and Distal Radius (Bottom) scans. Lines show cortical bone periosteal and endosteal semi-automatic segmentation. c 3-Dimensional reconstructed images of MH (top) and UUD (bottom) scans of a non-RA participant, with the cortical bone and trabecular bone regions separately reconstructed

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