Fig. 2
From: Quantitative evaluation of subchondral bone microarchitecture in knee osteoarthritis using 3T MRI
Image processing steps. 1). In vivo raw MR sagittal images in the center of the medial knee joint (a) and the lateral knee joint (h). 2). Correction of signal intensity variations and image artifacts (b, i). 3). Establishment of the ROI of subchondral bone (c, j). 4). Generation of the bone volume fraction map of a single slice (d, k). 5). Image thinning for the topological analysis (e, l). 6) Generation of a 3D BVF map (m)