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Fig. 1 | BMC Musculoskeletal Disorders

Fig. 1

From: Sequential activation of the AKT pathway in human osteoblasts treated with Oscarvit: a bioactive product with positive effect both on skeletal pain and mineralization in osteoblasts

Fig. 1

Morphological and immunocytochemical characteristics of osteoblasts from a primary culture. a Scanning electron micrograph demonstrating the architecture of a flattened fibroblast-like osteoblast with several fiber-like extensions. Strong accumulation of alkaline phosphatase (b1) and collagen type-1 (c1) are exhibited in human osteoblasts cells in contrast to normal fibroblasts (b2 and c2). Osteoblasts demonstrate expression of BGLAP (arrows) (d1), whereas no immunoreactivity of this marker protein was detectable in normal dermal fibroblasts (d2)

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