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Table 2 Included studies in alphabetic order according to inclusion and exclusion criteria

From: Infection following fractures of the proximal tibia – a systematic review of incidence and outcome

author

PMID / DOI

study design

level of evidence

n

classification

open fractures included y/n

open fractures

%

infection y/n

number infection

%

deep infection y/n

number deep infection

% DI

Revision because of infection

Outcome

Babis [29]

21756337

retrospective case series

4

33

Schatzker

y

5

15.2

y

1

3.0

y

1

3

y

septic pseudarthrosis 1

Barei [30]

16882892

retrospective case series

4

83

AO

y

11

13.0

y

5

6.0

y

2

2,4

y

union 2

Barei [31]

15507817

retrospective case series

4

83

AO

y

11

13.3

y

15

18.1

y

7

8,4

y

union 7

Berber [32]

24377482

retrospective case series

4

16

Schatzker

y

2

12.5

y

2

12.5

n

0

0

n

good 2

Biggi [33]

20888560

retrospective case series

4

58

AO

y

3

5.2

y

4

6.9

y

1

1,7

y

good 1

Bucholz [34]

2537166

randomized controlled trial

1

40

Hohl

n

0

0

y

4

10.0

y

4

10

y

good 3 persistent infection 1

Chakraverty [35]

19516098

retrospective case series

4

16

AO

y

3

18.8

y

2

12.5

y

2

12,5

y

amputation 1 persistent infection 1

Cole [36]

15475848

retrospective case series

4

78

AO

y

22

28.2

y

2

2.6

y

2

2,6

y

union 2

Conserva [37]

26243524

retrospective case series

4

79

Schatzker

n

0

0

y

11

13.9

y

6

7,6

y

arthroplasty 1 good 5

Dallo’Oca [38]

23086660

retrospective case series

4

100

Schatzker

n

0

0

y

4

4.0

y

2

2

y

arthroplasty 1 persistent infection 1

Egol [39]

16056075

retrospective case series

4

53

Schatzker

y

16

30.2

y

3

5.7

y

3

5,7

y

nonunion 1 union 2

Engelbrecht [40]

4648423

retrospective case series

4

194

not mentioned

n

0

0

y

6

3.1

y

6

3,1

y

ankylosis 2 persistent fistula 1 union 3

Hadiukenych [41]

17332111

retrospective case series

4

54

AO

y

12

21.0

y

3

5.6

y

2

3,7

y

amputation 1 nonunion 1

Hutson [42]

9553864

prospective cohort

3

70

AO

y

33

47.1

y

5

7.1

y

3

4,3

y

persistent oedema 1 amputation 1 persistent infection 1

Jansen [43]

23661179

retrospective case series

4

22

AO

y

6

26.1

y

4

17.0

y

2

9,1

y

pseudarthrosis 2

Khatri [44]

10.1155/2014/589538

retrospective case series

4

65

Schatzker

n

0

0

y

6

9.2

y

3

4,6

y

delayed union 2 nonunion 1

Lin [19]

23754632

retrospective case series

4

251

AO

y

30

11.7

y

20

7.8

y

16

6,4

y

nonunion 3 malalignement 1 union 12

Marsh [4]

7744891

prospective cohort

3

20

Schatzker

y

7

35.0

y

9

45.0

y

2

10

y

ankylosis 1 union 1

Neogi [45]

26015609

prospective cohort study

3

61

AO

y

10

16.4

y

7

11.5

y

1

1,6

y

Stiffness 1

Ozkaya [46]

26021666

retrospective case series

4

22

AO

n

0

0

y

4

18.2

y

1

4,5

y

stiffness 1

Phisitkul [3]

17304060

retrospective case series

4

37

AO

y

6

16.2

y

8

22.0

y

8

21,6

y

amputation 1 satisfactory 7

Pun [47]

24600061

prospective cohort study

3

21

Schatzker

y

4

19.0

y

2

9.5

n

0

0

n

good 2

Rademakers [48]

17211262

retrospective case series

4

202

AO

n

0

0

y

11

5.4

y

11

5,4

y

arthrodesis 2 union 9

Sales [49]

24498816

retrospective case series

4

28

Schatzker

y

9

32.1

y

7

25.0

n

0

0

n

good 7

Stannard [50]

19753230

retrospective case series

4

52

AO

y

52

100

y

6

11.5

y

3

5,8

y

amputation 1 nonunion 2

Stannard [51]

14563009

prospective cohort

3

32

Schatzker

y

17

53.1

y

2

6.3

y

2

6,3

y

nonunion 1 union 1

Su [52]

15123954

retrospective case series

4

38

Schatzker

y

1

2.6

y

3

7.7

y

1

2,6

y

union 1

Wagner [53]

3749907

retrospective case series

4

32

AO

n

0

0

y

6

18.8

y

6

18,8

y

ankolysis 1 arthrodesis 5

Weaver [54]

22169068

retrospective case series

4

140

AO

y

20

14.3

y

15

10.7

y

15

10,8

y

nonunion 7 malalignement 8

Young [55]

8196973

prospective cohort study

3

45

AO

y

9

20

y

13

28.9

y

13

28,9

y

amputation 2 arthrodesis 3 ankylosis 8

Zhai [56]

24346508

retrospective case series

4

26

AO

y

8

30.8

y

4

15.4

y

1

3,8

y

good 1

Zhang [57]

22385447

retrospective case series

4

79

AO

y

7

8.9

y

9

11.4

y

3

3,8

y

bone graft and muscle flap 3