Fig. 4
From: Establishment of rat ankle post-traumatic osteoarthritis model induced by malleolus fracture
Safranin-O staining and quantification of the histological results. a Unlike the control groups (a and d), OA changes were observed in fracture groups, including cartilage fibrillation and cranny, rough articular surface, the loss of Acan, matrix and chondrocytes (b-c and e-f). Particularly, OA lesions were more severe in the central cartilage when compared with the peripheral cartilage. b Quantification of the histological results obtained using the modified OARSI score; there was a significant statistical difference between surgical sides and control sides in both models. No difference was observed between the two models. Values are the mean ± SD, * = P < 0.05 versus controls