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Fig. 3 | BMC Musculoskeletal Disorders

Fig. 3

From: L161982 alleviates collagen-induced arthritis in mice by increasing Treg cells and down-regulating Interleukin-17 and monocyte-chemoattractant protein-1 levels

Fig. 3

Immunohistochemical staining of CIA-model mice for testing the tissue expression of MCP-1,IL-17 and C-caspase 3. Celecoxib and L161982 treated CIA mice showed lower level of MCP-1 and IL-17 than the blank and PBS group. The expression of C-caspase 3 in all groups were looked no difference. “N.C” i.e. negative control, means tissue were stained without the corresponding primary antibody. C-caspase 3 means cleaved caspase 3

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